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1999 1
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48 results

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Page 1
MAPK8IP2 is a potential prognostic biomarker and promote tumor progression in prostate cancer.
Zeng Z, He W, Jiang Y, Jiang H, Cheng X, Deng W, Zhou X, Zhang C, Wang G. Zeng Z, et al. BMC Cancer. 2022 Nov 11;22(1):1162. doi: 10.1186/s12885-022-10259-2. BMC Cancer. 2022. PMID: 36357836 Free PMC article.
MAPK8IP2 has been reported to be closely associated with several cancers. However, the biological function of MAPK8IP2 in prostate cancer (PCa) remains unclear. ...The MAPK8IP2 genetic alteration rate was 2.6% and MAPK8IP2 alterations correlated with a
MAPK8IP2 has been reported to be closely associated with several cancers. However, the biological function of MAPK8IP2 in pros
Scaffold protein MAPK8IP2 expression is a robust prognostic factor in prostate cancer associated with AR signaling activity.
Huang J, Liu W, Lin BY, Li JC, Lu J, Li BY. Huang J, et al. Asian J Androl. 2023 Mar-Apr;25(2):198-207. doi: 10.4103/aja202240. Asian J Androl. 2023. PMID: 35975362 Free PMC article.
Mitogen-activated protein kinase-8-interacting protein 2 (MAPK8IP2) is a scaffold protein that modulates MAPK signal cascades. Although MAPK pathways were heavily implicated in prostate cancer progression, the regulation of MAPK8IP2 expression in prostate cancer is …
Mitogen-activated protein kinase-8-interacting protein 2 (MAPK8IP2) is a scaffold protein that modulates MAPK signal cascades. Althou …
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis.
Zhenhao Z, Ru C, Xiaofeng C, Heng Y, Gongxian W. Zhenhao Z, et al. Cell Death Discov. 2023 Dec 14;9(1):455. doi: 10.1038/s41420-023-01750-1. Cell Death Discov. 2023. PMID: 38097567 Free PMC article.
Mechanistically, circMAML3 promotes prostate cancer progression by upregulating MAPK8IP2 expression through sponge miR-665. Our research indicates that circMAML3 promotes prostate cancer progression through the circMAML3/miR-665/MAPK8IP2 axis. circMAML3 and MAPK8
Mechanistically, circMAML3 promotes prostate cancer progression by upregulating MAPK8IP2 expression through sponge miR-665. Our resea …
Evaluation of PKM2 and MAPK8IP2 Polymorphism in Ameloblastic Carcinoma: A Retrospective Quantitative Study.
Khodayari A, Ghaderian SM, Jafarian M, Jahangirnia A, Nayebi A, Akhlaghi F, Taghavi N, Akbarzadeh Najar R, Tabarestani S, Khojasteh A, Aghabozorg Afjeh S. Khodayari A, et al. Int J Mol Cell Med. 2012 Fall;1(4):203-9. Int J Mol Cell Med. 2012. PMID: 24551779 Free PMC article.
We report a case series study of ameloblastic carcinoma and ameloblastoma to show the role of PKM2 and MAPK8IP2 polymorphisms in these tumors. The DNA was extracted separately from specimens in paraffin sections of the tumor. ...
We report a case series study of ameloblastic carcinoma and ameloblastoma to show the role of PKM2 and MAPK8IP2 polymorphisms in thes …
Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following liver injury.
Guillot A, Guerri L, Feng D, Kim SJ, Ahmed YA, Paloczi J, He Y, Schuebel K, Dai S, Liu F, Pacher P, Kisseleva T, Qin X, Goldman D, Tacke F, Gao B. Guillot A, et al. J Clin Invest. 2021 May 3;131(9):e132305. doi: 10.1172/JCI132305. J Clin Invest. 2021. PMID: 33724957 Free PMC article.
Using microdissection and next-generation RNA-Seq, we identified 5 genes, including Mapk8ip2, Cdkn1a, Itgb6, Rgs4, and Ccl2, that were most upregulated in proliferating BECs after acute injury. ...
Using microdissection and next-generation RNA-Seq, we identified 5 genes, including Mapk8ip2, Cdkn1a, Itgb6, Rgs4, and Ccl2, that wer …
SLAMF1 as a novel molecule mediating the causal association between rheumatoid arthritis and interstitial lung disease: A Mendelian randomization study combined with transcriptomics and in vivo validation.
Liu M, Jiang Z, Liu M, Ni H, Li Y, Fang J, Du Q, Dong Y. Liu M, et al. Int Immunopharmacol. 2024 Dec 5;142(Pt A):113082. doi: 10.1016/j.intimp.2024.113082. Epub 2024 Sep 10. Int Immunopharmacol. 2024. PMID: 39260308
Furthermore, integrated bioinformatic analyses were conducted to elucidate the specific biological functions of the determined mediator in pathogenesis of RA-ILD. RESULTS: Nine genes, namely MAPK8IP2, TAF11, SLAMF1, DAB2IP, GLUL, SLC4A10, PRSS35, NFX1, and PLK3, were ident …
Furthermore, integrated bioinformatic analyses were conducted to elucidate the specific biological functions of the determined mediator in p …
P38-β/SAPK-inhibiting and apoptosis-inducing activities of (E)-4-chloro-2-((3-ethoxy-2-hydroxybenzylidene) amino)phenol.
Karaosmanoğlu O. Karaosmanoğlu O. Hum Exp Toxicol. 2020 Oct;39(10):1374-1389. doi: 10.1177/0960327120924112. Epub 2020 May 12. Hum Exp Toxicol. 2020. PMID: 32394730
In addition, ACES induced apoptosis by nuclear fragmentation, MMP disruption, and intracellular ROS elevation in MCF-7 cells. qRT-PCR experiment indicated the expressions of 30 genes including ATF2, CREB1, MYC, NFATC4 (NFAT3), CCNA1, CCNB1, CCND2, CDK2, CDKN1A (p21CIP1), CDKN1C ( …
In addition, ACES induced apoptosis by nuclear fragmentation, MMP disruption, and intracellular ROS elevation in MCF-7 cells. qRT-PCR experi …
Kinesin carries the signal.
Verhey KJ, Rapoport TA. Verhey KJ, et al. Trends Biochem Sci. 2001 Sep;26(9):545-50. doi: 10.1016/s0968-0004(01)01931-4. Trends Biochem Sci. 2001. PMID: 11551791 Review.
Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB.
Alhosani F, Ilce BY, Alhamidi RS, Bhamidimarri PM, Hamad AM, Alkhayyal N, Künstner A, Khandanpour C, Busch H, Al-Ramadi B, Sayed K, AlFazari A, Bendardaf R, Hamoudi R. Alhosani F, et al. Int J Mol Sci. 2024 Sep 26;25(19):10367. doi: 10.3390/ijms251910367. Int J Mol Sci. 2024. PMID: 39408697 Free PMC article.
Carcinoma patients showed a dramatic increase in the expression of MAPK8IP2 in CARD11+ carcinoma patients alongside other cancer-related genes, including EMB, EPHB6, and CPEB4....
Carcinoma patients showed a dramatic increase in the expression of MAPK8IP2 in CARD11+ carcinoma patients alongside other cancer-rela …
Regulation of the COPII secretory machinery via focal adhesions and extracellular matrix signaling.
Jung J, Khan MM, Landry J, Halavatyi A, Machado P, Reiss M, Pepperkok R. Jung J, et al. J Cell Biol. 2022 Aug 1;221(8):e202110081. doi: 10.1083/jcb.202110081. Epub 2022 Jul 13. J Cell Biol. 2022. PMID: 35829701 Free PMC article.
Among these, we identified a group of proteins associated with focal adhesions (FERMT2, MACF1, MAPK8IP2, NGEF, PIK3CA, and ROCK1) that led to the downregulation of SEC23A when depleted by siRNA. ...
Among these, we identified a group of proteins associated with focal adhesions (FERMT2, MACF1, MAPK8IP2, NGEF, PIK3CA, and ROCK1) tha …
48 results