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Deciphering the roadmap of in vivo reprogramming toward pluripotency.
Chondronasiou D, Martínez de Villarreal J, Melendez E, Lynch CJ, Pozo ND, Kovatcheva M, Aguilera M, Prats N, Real FX, Serrano M. Chondronasiou D, et al. Among authors: martinez de villarreal j. Stem Cell Reports. 2022 Nov 8;17(11):2501-2517. doi: 10.1016/j.stemcr.2022.09.009. Epub 2022 Oct 20. Stem Cell Reports. 2022. PMID: 36270281 Free PMC article.
Natural killer cells act as an extrinsic barrier for in vivo reprogramming.
Melendez E, Chondronasiou D, Mosteiro L, Martínez de Villarreal J, Fernández-Alfara M, Lynch CJ, Grimm D, Real FX, Alcamí J, Climent N, Pietrocola F, Serrano M. Melendez E, et al. Among authors: martinez de villarreal j. Development. 2022 Apr 15;149(8):dev200361. doi: 10.1242/dev.200361. Epub 2022 Apr 22. Development. 2022. PMID: 35420133 Free PMC article.
A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer.
Kloesch B, Ionasz V, Paliwal S, Hruschka N, Martinez de Villarreal J, Öllinger R, Mueller S, Dienes HP, Schindl M, Gruber ES, Stift J, Herndler-Brandstetter D, Lomberk GA, Seidler B, Saur D, Rad R, Urrutia RA, Real FX, Martinelli P. Kloesch B, et al. Among authors: martinez de villarreal j. Gut. 2022 Apr;71(4):766-777. doi: 10.1136/gutjnl-2020-321397. Epub 2021 Apr 12. Gut. 2022. PMID: 33846140 Free PMC article.
Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors.
Garcia-Carbonero R, Bazan-Peregrino M, Gil-Martín M, Álvarez R, Macarulla T, Riesco-Martinez MC, Verdaguer H, Guillén-Ponce C, Farrera-Sal M, Moreno R, Mato-Berciano A, Maliandi MV, Torres-Manjon S, Costa M, Del Pozo N, Martínez de Villarreal J, Real FX, Vidal N, Capella G, Alemany R, Blasi E, Blasco C, Cascalló M, Salazar R. Garcia-Carbonero R, et al. Among authors: martinez de villarreal j. J Immunother Cancer. 2022 Mar;10(3):e003255. doi: 10.1136/jitc-2021-003255. J Immunother Cancer. 2022. PMID: 35338084 Free PMC article.
Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features.
Marqués M, Tranchant R, Risa-Ebrí B, Suárez-Solís ML, Fernández LC, Carrillo-de-Santa-Pau E, Del Pozo N, Martínez de Villarreal J, Meiller C, Allory Y, Blum Y, Pirker C, Hegedus B, Barry ST, Carnero A, Berger W, Jean D, Real FX. Marqués M, et al. Among authors: martinez de villarreal j. Cancer Res. 2020 Feb 15;80(4):843-856. doi: 10.1158/0008-5472.CAN-19-1633. Epub 2020 Jan 7. Cancer Res. 2020. PMID: 31911549 Free article.
BPTF cooperates with MYCN and MYC to link neuroblastoma cell cycle control to epigenetic cellular states.
Felipe I, Martínez-de-Villarreal J, Patel K, Martínez-Torrecuadrada J, Grossmann LD, Roncador G, Cubells M, Farrell A, Kendsersky N, Sabroso-Lasa S, Sancho-Temiño L, Torres K, Martinez D, Perez JM, García F, Pogoriler J, Moreno L, Maris JM, Real FX. Felipe I, et al. Among authors: martinez de villarreal j. bioRxiv [Preprint]. 2024 Feb 12:2024.02.11.579816. doi: 10.1101/2024.02.11.579816. bioRxiv. 2024. PMID: 38405949 Free PMC article. Preprint.