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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2004 1
2005 4
2006 8
2007 1
2008 1
2009 3
2010 17
2011 13
2012 15
2013 13
2014 8
2015 5
2016 7
2017 6
2018 7
2019 4
2020 3
2021 5
2022 10
2023 6
2024 4

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114 results

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Page 1
The Impact of Assay Design on Medicinal Chemistry: Case Studies.
Born JR, Chenniappan VK, Davis DP, Dahlin JL, Marugan JJ, Patnaik S. Born JR, et al. Among authors: marugan jj. SLAS Discov. 2021 Dec;26(10):1243-1255. doi: 10.1177/24725552211026238. Epub 2021 Jul 5. SLAS Discov. 2021. PMID: 34225522 Free article. Review.
c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's disease.
León R, Gutiérrez DA, Pinto C, Morales C, de la Fuente C, Riquelme C, Cortés BI, González-Martin A, Chamorro D, Espinosa N, Fuentealba P, Cancino GI, Zanlungo S, Dulcey AE, Marugan JJ, Álvarez Rojas A. León R, et al. Among authors: marugan jj. Front Aging Neurosci. 2023 Jun 5;15:1180987. doi: 10.3389/fnagi.2023.1180987. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37358955 Free PMC article.
Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Kaftanovskaya EM, Ng HH, Soula M, Rivas B, Myhr C, Ho BA, Cervantes BA, Shupe TD, Devarasetty M, Hu X, Xu X, Patnaik S, Wilson KJ, Barnaeva E, Ferrer M, Southall NT, Marugan JJ, Bishop CE, Agoulnik IU, Agoulnik AI. Kaftanovskaya EM, et al. Among authors: marugan jj. FASEB J. 2019 Nov;33(11):12435-12446. doi: 10.1096/fj.201901046R. Epub 2019 Aug 16. FASEB J. 2019. PMID: 31419161 Free PMC article.
Discovery of Small Molecule Influenza Virus NS1 Antagonist.
Patnaik S, Basu D, Dehdashti S, Zheng W, Ferrer M, Southall N, Taylor M, Engel DA, Marugan JJ. Patnaik S, et al. Among authors: marugan jj. 2012 Apr 13 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 13 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24260784 Free Books & Documents. Review.
The pilot phase of the NIH Chemical Genomics Center.
Thomas CJ, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan JJ, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin CP. Thomas CJ, et al. Among authors: marugan jj. Curr Top Med Chem. 2009;9(13):1181-93. doi: 10.2174/156802609789753644. Curr Top Med Chem. 2009. PMID: 19807664 Free PMC article. Review.
A combinatorial approach increases SMN level in SMA model mice.
Dumas SA, Villalón E, Bergman EM, Wilson KJ, Marugan JJ, Lorson CL, Burnett BG. Dumas SA, et al. Among authors: marugan jj. Hum Mol Genet. 2022 Aug 25;31(17):2989-3000. doi: 10.1093/hmg/ddac068. Hum Mol Genet. 2022. PMID: 35419606 Free PMC article.
Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
Liu L, Tang M, Pragani R, Whitby FG, Zhang YQ, Balakrishnan B, Fang Y, Karavadhi S, Tao D, LeClair CA, Hall MD, Marugan JJ, Boxer M, Shen M, Hill CP, Lai K, Patnaik S. Liu L, et al. Among authors: marugan jj. J Med Chem. 2021 Sep 23;64(18):13551-13571. doi: 10.1021/acs.jmedchem.1c00945. Epub 2021 Sep 7. J Med Chem. 2021. PMID: 34491744 Free PMC article.
Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.
Sanchez TW, Ronzetti MH, Owens AE, Antony M, Voss T, Wallgren E, Talley D, Balakrishnan K, Leyes Porello SE, Rai G, Marugan JJ, Michael SG, Baljinnyam B, Southall N, Simeonov A, Henderson MJ. Sanchez TW, et al. Among authors: marugan jj. ACS Chem Biol. 2022 Sep 16;17(9):2471-2482. doi: 10.1021/acschembio.2c00334. Epub 2022 Sep 1. ACS Chem Biol. 2022. PMID: 36049119 Free PMC article.
Identification of compounds which inhibit cytotoxicity associated with mutant Huntingtin protein expression.
Titus S, Elia N, Southall N, Zheng W, Marugan JJ, MacDonald M. Titus S, et al. Among authors: marugan jj. 2010 Mar 30 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Mar 30 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735602 Free Books & Documents. Review.
114 results