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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2004 1
2005 4
2006 8
2007 1
2008 1
2009 3
2010 17
2011 13
2012 15
2013 13
2014 8
2015 5
2016 7
2017 6
2018 7
2019 4
2020 3
2021 5
2022 10
2023 1
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Search Results

105 results
Results by year
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Page 1
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease.
Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, Ory DS, Marugan JJ, Zheng W. Vu M, et al. Among authors: marugan jj. Orphanet J Rare Dis. 2018 Sep 17;13(1):152. doi: 10.1186/s13023-018-0886-3. Orphanet J Rare Dis. 2018. PMID: 30220252 Free PMC article.
Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Kaftanovskaya EM, Ng HH, Soula M, Rivas B, Myhr C, Ho BA, Cervantes BA, Shupe TD, Devarasetty M, Hu X, Xu X, Patnaik S, Wilson KJ, Barnaeva E, Ferrer M, Southall NT, Marugan JJ, Bishop CE, Agoulnik IU, Agoulnik AI. Kaftanovskaya EM, et al. Among authors: marugan jj. FASEB J. 2019 Nov;33(11):12435-12446. doi: 10.1096/fj.201901046R. Epub 2019 Aug 16. FASEB J. 2019. PMID: 31419161 Free PMC article.
The Impact of Assay Design on Medicinal Chemistry: Case Studies.
Born JR, Chenniappan VK, Davis DP, Dahlin JL, Marugan JJ, Patnaik S. Born JR, et al. Among authors: marugan jj. SLAS Discov. 2021 Dec;26(10):1243-1255. doi: 10.1177/24725552211026238. Epub 2021 Jul 5. SLAS Discov. 2021. PMID: 34225522 Free article. Review.
A combinatorial approach increases SMN level in SMA model mice.
Dumas SA, Villalón E, Bergman EM, Wilson KJ, Marugan JJ, Lorson CL, Burnett BG. Dumas SA, et al. Among authors: marugan jj. Hum Mol Genet. 2022 Aug 25;31(17):2989-3000. doi: 10.1093/hmg/ddac068. Hum Mol Genet. 2022. PMID: 35419606
Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.
Sanchez TW, Ronzetti MH, Owens AE, Antony M, Voss T, Wallgren E, Talley D, Balakrishnan K, Leyes Porello SE, Rai G, Marugan JJ, Michael SG, Baljinnyam B, Southall N, Simeonov A, Henderson MJ. Sanchez TW, et al. Among authors: marugan jj. ACS Chem Biol. 2022 Sep 16;17(9):2471-2482. doi: 10.1021/acschembio.2c00334. Epub 2022 Sep 1. ACS Chem Biol. 2022. PMID: 36049119 Free PMC article.
Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
Liu L, Tang M, Pragani R, Whitby FG, Zhang YQ, Balakrishnan B, Fang Y, Karavadhi S, Tao D, LeClair CA, Hall MD, Marugan JJ, Boxer M, Shen M, Hill CP, Lai K, Patnaik S. Liu L, et al. Among authors: marugan jj. J Med Chem. 2021 Sep 23;64(18):13551-13571. doi: 10.1021/acs.jmedchem.1c00945. Epub 2021 Sep 7. J Med Chem. 2021. PMID: 34491744 Free PMC article.
Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.
Esteban-Lopez M, Wilson KJ, Myhr C, Kaftanovskaya EM, Henderson MJ, Southall NT, Xu X, Wang A, Hu X, Barnaeva E, Ye W, George ER, Sherrill JT, Ferrer M, Morello R, Agoulnik IU, Marugan JJ, Agoulnik AI. Esteban-Lopez M, et al. Among authors: marugan jj. Commun Biol. 2022 Nov 4;5(1):1183. doi: 10.1038/s42003-022-04143-9. Commun Biol. 2022. PMID: 36333465 Free PMC article.
Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.
Chen FW, Davies JP, Calvo R, Chaudhari J, Dolios G, Taylor MK, Patnaik S, Dehdashti J, Mull R, Dranchack P, Wang A, Xu X, Hughes E, Southall N, Ferrer M, Wang R, Marugan JJ, Ioannou YA. Chen FW, et al. Among authors: marugan jj. iScience. 2022 Aug 14;25(9):104941. doi: 10.1016/j.isci.2022.104941. eCollection 2022 Sep 16. iScience. 2022. PMID: 36065186 Free PMC article.
105 results