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Page 1
Sodium ion binding pocket mutations and adenosine A2A receptor function.
Massink A, Gutiérrez-de-Terán H, Lenselink EB, Ortiz Zacarías NV, Xia L, Heitman LH, Katritch V, Stevens RC, IJzerman AP. Massink A, et al. Mol Pharmacol. 2015 Feb;87(2):305-13. doi: 10.1124/mol.114.095737. Epub 2014 Dec 3. Mol Pharmacol. 2015. PMID: 25473121 Free PMC article.
The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor.
Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. Gutiérrez-de-Terán H, et al. Among authors: massink a. Structure. 2013 Dec 3;21(12):2175-85. doi: 10.1016/j.str.2013.09.020. Epub 2013 Nov 7. Structure. 2013. PMID: 24210756 Free PMC article.
Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Romagnoli R, Baraldi PG, Lopez-Cara C, Cruz-Lopez O, Moorman AR, Massink A, IJzerman AP, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: massink a. Eur J Med Chem. 2015 Aug 28;101:185-204. doi: 10.1016/j.ejmech.2015.06.041. Epub 2015 Jun 24. Eur J Med Chem. 2015. PMID: 26141910
Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene.
Romagnoli R, Baraldi PG, IJzerman AP, Massink A, Cruz-Lopez O, Lopez-Cara LC, Saponaro G, Preti D, Aghazadeh Tabrizi M, Baraldi S, Moorman AR, Vincenzi F, Borea PA, Varani K. Romagnoli R, et al. Among authors: massink a. J Med Chem. 2014 Sep 25;57(18):7673-86. doi: 10.1021/jm5008853. Epub 2014 Sep 12. J Med Chem. 2014. PMID: 25181013