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Innate inflammation drives NK cell activation to impair Treg activity.

Dean JW, Peters LD, Fuhrman CA, Seay HR, Posgai AL, Stimpson SE, Brusko MA, Perry DJ, Yeh WI, Newby BN, Haller MJ, Muir AB, Atkinson MA, Mathews CE, Brusko TM. Dean JW, et al. Among authors: mathews ce. J Autoimmun. 2020 Mar;108:102417. doi: 10.1016/j.jaut.2020.102417. Epub 2020 Feb 6. J Autoimmun. 2020. PMID: 32035746 Free PMC article.

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Mitochondrial Reactive Oxygen Species and Type 1 Diabetes.

Chen J, Stimpson SE, Fernandez-Bueno GA, Mathews CE. Chen J, et al. Among authors: mathews ce. Antioxid Redox Signal. 2018 Nov 10;29(14):1361-1372. doi: 10.1089/ars.2017.7346. Epub 2018 Feb 15. Antioxid Redox Signal. 2018. PMID: 29295631 Free PMC article. Review.

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Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes.

Jacobsen LM, Bundy BN, Greco MN, Schatz DA, Atkinson MA, Brusko TM, Mathews CE, Herold KC, Gitelman SE, Krischer JP, Haller MJ. Jacobsen LM, et al. Among authors: mathews ce. Diabetes Technol Ther. 2020 Dec;22(12):948-953. doi: 10.1089/dia.2020.0305. Epub 2020 Oct 20. Diabetes Technol Ther. 2020. PMID: 32833543 Free PMC article.

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Nanodroplet processing platform for deep and quantitative proteome profiling of 10-100 mammalian cells.

Zhu Y, Piehowski PD, Zhao R, Chen J, Shen Y, Moore RJ, Shukla AK, Petyuk VA, Campbell-Thompson M, Mathews CE, Smith RD, Qian WJ, Kelly RT. Zhu Y, et al. Among authors: mathews ce. Nat Commun. 2018 Feb 28;9(1):882. doi: 10.1038/s41467-018-03367-w. Nat Commun. 2018. PMID: 29491378 Free PMC article.

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Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD.

Muyyarikkandy MS, McLeod M, Maguire M, Mahar R, Kattapuram N, Zhang C, Surugihalli C, Muralidaran V, Vavilikolanu K, Mathews CE, Merritt ME, Sunny NE. Muyyarikkandy MS, et al. Among authors: mathews ce. FASEB J. 2020 Nov;34(11):14832-14849. doi: 10.1096/fj.202001495R. Epub 2020 Sep 12. FASEB J. 2020. PMID: 32918763 Free PMC article.

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NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8⁺ T-Cell Numbers.

Trembath AP, Krausz KL, Sharma N, Gerling IC, Mathews CE, Markiewicz MA. Trembath AP, et al. Among authors: mathews ce. Diabetes. 2020 Aug;69(8):1749-1762. doi: 10.2337/db19-0979. Epub 2020 Jun 13. Diabetes. 2020. PMID: 32535552 Free article.

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Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes.

Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG. Richardson SJ, et al. Among authors: mathews ce. Diabetologia. 2016 Nov;59(11):2448-2458. doi: 10.1007/s00125-016-4067-4. Epub 2016 Aug 9. Diabetologia. 2016. PMID: 27506584 Free PMC article.

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Lipid mediators and biomarkers associated with type 1 diabetes development.

Nelson AJ, Stephenson DJ, Bone RN, Cardona CL, Park MA, Tusing YG, Lei X, Kokotos G, Graves CL, Mathews CE, Kramer J, Hessner MJ, Chalfant CE, Ramanadham S. Nelson AJ, et al. Among authors: mathews ce. JCI Insight. 2020 Aug 20;5(16):e138034. doi: 10.1172/jci.insight.138034. JCI Insight. 2020. PMID: 32814707 Free PMC article.

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Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice.

Eudy BJ, McDermott CE, Fernandez G, Mathews CE, Lai J, da Silva RP. Eudy BJ, et al. Among authors: mathews ce. J Nutr Biochem. 2020 Jul;81:108381. doi: 10.1016/j.jnutbio.2020.108381. Epub 2020 Mar 19. J Nutr Biochem. 2020. PMID: 32422424 Free PMC article.

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Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment.

Newby BN, Mathews CE. Newby BN, et al. Among authors: mathews ce. Front Endocrinol (Lausanne). 2017 Sep 14;8:232. doi: 10.3389/fendo.2017.00232. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 28959234 Free PMC article. Review.

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