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Human muscle stem cells are refractory to aging.

Novak JS, Mázala DAG, Nearing M, Hindupur R, Uapinyoying P, Habib NF, Dickson T, Ioffe OB, Harris BT, Fidelia-Lambert MN, Rossi CT, Hill DA, Wagner KR, Hoffman EP, Partridge TA. Novak JS, et al. Among authors: mazala dag. Aging Cell. 2021 Jul;20(7):e13411. doi: 10.1111/acel.13411. Epub 2021 Jun 5. Aging Cell. 2021. PMID: 34089289 Free PMC article.

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Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair.

Chandra G, Sreetama SC, Mázala DAG, Charton K, VanderMeulen JH, Richard I, Jaiswal JK. Chandra G, et al. Among authors: mazala dag. J Cell Biol. 2021 May 3;220(5):e202006035. doi: 10.1083/jcb.202006035. J Cell Biol. 2021. PMID: 33688936 Free PMC article.

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Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy.

Novak JS, Spathis R, Dang UJ, Fiorillo AA, Hindupur R, Tully CB, Mázala DAG, Canessa E, Brown KJ, Partridge TA, Hathout Y, Nagaraju K. Novak JS, et al. Among authors: mazala dag. J Neuromuscul Dis. 2021;8(s2):S383-S402. doi: 10.3233/JND-210696. J Neuromuscul Dis. 2021. PMID: 34569969 Free PMC article.

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Coping with the calcium overload caused by cell injury: ER to the rescue.

Chandra G, Mázala DAG, Jaiswal JK. Chandra G, et al. Among authors: mazala dag. Cell Stress. 2021 Apr 16;5(5):73-75. doi: 10.15698/cst2021.05.249. Cell Stress. 2021. PMID: 33987529 Free PMC article.

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TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model.

Mázala DA, Novak JS, Hogarth MW, Nearing M, Adusumalli P, Tully CB, Habib NF, Gordish-Dressman H, Chen YW, Jaiswal JK, Partridge TA. Mázala DA, et al. JCI Insight. 2020 Mar 26;5(6):e135703. doi: 10.1172/jci.insight.135703. JCI Insight. 2020. PMID: 32213706 Free PMC article.

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Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy.

Heier CR, Yu Q, Fiorillo AA, Tully CB, Tucker A, Mazala DA, Uaesoontrachoon K, Srinivassane S, Damsker JM, Hoffman EP, Nagaraju K, Spurney CF. Heier CR, et al. Among authors: mazala da. Life Sci Alliance. 2019 Feb 11;2(1):e201800186. doi: 10.26508/lsa.201800186. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30745312 Free PMC article.

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Pathogenic role and therapeutic potential of fibro-adipogenic progenitors in muscle disease.

Hogarth MW, Uapinyoying P, Mázala DAG, Jaiswal JK. Hogarth MW, et al. Among authors: mazala dag. Trends Mol Med. 2022 Jan;28(1):8-11. doi: 10.1016/j.molmed.2021.10.003. Epub 2021 Nov 5. Trends Mol Med. 2022. PMID: 34750068

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Dysregulation of Mitochondrial Ca²⁺ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1.

Debattisti V, Horn A, Singh R, Seifert EL, Hogarth MW, Mazala DA, Huang KT, Horvath R, Jaiswal JK, Hajnóczky G. Debattisti V, et al. Among authors: mazala da. Cell Rep. 2019 Oct 29;29(5):1274-1286.e6. doi: 10.1016/j.celrep.2019.09.063. Cell Rep. 2019. PMID: 31665639 Free PMC article.

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Defects in sarcolemma repair and skeletal muscle function after injury in a mouse model of Niemann-Pick type A/B disease.

Michailowsky V, Li H, Mittra B, Iyer SR, Mazála DAG, Corrotte M, Wang Y, Chin ER, Lovering RM, Andrews NW. Michailowsky V, et al. Among authors: mazala dag. Skelet Muscle. 2019 Jan 5;9(1):1. doi: 10.1186/s13395-018-0187-5. Skelet Muscle. 2019. PMID: 30611303 Free PMC article.

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Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis.

Amici DR, Pinal-Fernandez I, Mázala DA, Lloyd TE, Corse AM, Christopher-Stine L, Mammen AL, Chin ER. Amici DR, et al. Among authors: mazala da. Acta Neuropathol Commun. 2017 Mar 22;5(1):24. doi: 10.1186/s40478-017-0427-7. Acta Neuropathol Commun. 2017. PMID: 28330496 Free PMC article.

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