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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1996 1
1998 1
1999 2
2002 1
2004 2
2005 1
2006 2
2007 1
2009 2
2010 1
2011 4
2012 4
2013 4
2014 3
2015 1
2016 1
2017 2
2018 4
2019 2
2020 1
2021 1
2022 0
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37 results
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Page 1
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
Gopalsamy A, Aulabaugh AE, Barakat A, Beaumont KC, Cabral S, Canterbury DP, Casimiro-Garcia A, Chang JS, Chen MZ, Choi C, Dow RL, Fadeyi OO, Feng X, France SP, Howard RM, Janz JM, Jasti J, Jasuja R, Jones LH, King-Ahmad A, Knee KM, Kohrt JT, Limberakis C, Liras S, Martinez CA, McClure KF, Narayanan A, Narula J, Novak JJ, O'Connell TN, Parikh MD, Piotrowski DW, Plotnikova O, Robinson RP, Sahasrabudhe PV, Sharma R, Thuma BA, Vasa D, Wei L, Wenzel AZ, Withka JM, Xiao J, Yayla HG. Gopalsamy A, et al. Among authors: mcclure kf. J Med Chem. 2021 Jan 14;64(1):326-342. doi: 10.1021/acs.jmedchem.0c01518. Epub 2020 Dec 24. J Med Chem. 2021. PMID: 33356244
Benzimidazolone p38 inhibitors.
Dombroski MA, Letavic MA, McClure KF, Barberia JT, Carty TJ, Cortina SR, Csiki C, Dipesa AJ, Elliott NC, Gabel CA, Jordan CK, Labasi JM, Martin WH, Peese KM, Stock IA, Svensson L, Sweeney FJ, Yu CH. Dombroski MA, et al. Among authors: mcclure kf. Bioorg Med Chem Lett. 2004 Feb 23;14(4):919-23. doi: 10.1016/j.bmcl.2003.12.023. Bioorg Med Chem Lett. 2004. PMID: 15012994
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.
Rouet R, Thuma BA, Roy MD, Lintner NG, Rubitski DM, Finley JE, Wisniewska HM, Mendonsa R, Hirsh A, de Oñate L, Compte Barrón J, McLellan TJ, Bellenger J, Feng X, Varghese A, Chrunyk BA, Borzilleri K, Hesp KD, Zhou K, Ma N, Tu M, Dullea R, McClure KF, Wilson RC, Liras S, Mascitti V, Doudna JA. Rouet R, et al. Among authors: mcclure kf. J Am Chem Soc. 2018 May 30;140(21):6596-6603. doi: 10.1021/jacs.8b01551. Epub 2018 May 18. J Am Chem Soc. 2018. PMID: 29668265 Free PMC article.
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.
McClure KF, Piotrowski DW, Petersen D, Wei L, Xiao J, Londregan AT, Kamlet AS, Dechert-Schmitt AM, Raymer B, Ruggeri RB, Canterbury D, Limberakis C, Liras S, DaSilva-Jardine P, Dullea RG, Loria PM, Reidich B, Salatto CT, Eng H, Kimoto E, Atkinson K, King-Ahmad A, Scott D, Beaumont K, Chabot JR, Bolt MW, Maresca K, Dahl K, Arakawa R, Takano A, Halldin C. McClure KF, et al. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16218-16222. doi: 10.1002/anie.201708744. Epub 2017 Nov 24. Angew Chem Int Ed Engl. 2017. PMID: 29073340
Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents.
Londregan AT, Wei L, Xiao J, Lintner NG, Petersen D, Dullea RG, McClure KF, Bolt MW, Warmus JS, Coffey SB, Limberakis C, Genovino J, Thuma BA, Hesp KD, Aspnes GE, Reidich B, Salatto CT, Chabot JR, Cate JHD, Liras S, Piotrowski DW. Londregan AT, et al. Among authors: mcclure kf. J Med Chem. 2018 Jul 12;61(13):5704-5718. doi: 10.1021/acs.jmedchem.8b00650. Epub 2018 Jun 25. J Med Chem. 2018. PMID: 29878763
Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.
Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, Xiao J, Bolt M, Loria PM, Maguire B, Geoghegan KF, Huang A, Rolph T, Liras S, Doudna JA, Dullea RG, Cate JH. Lintner NG, et al. Among authors: mcclure kf. PLoS Biol. 2017 Mar 21;15(3):e2001882. doi: 10.1371/journal.pbio.2001882. eCollection 2017 Mar. PLoS Biol. 2017. PMID: 28323820 Free PMC article.
Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.
Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, Xiao J, Bolt M, Loria PM, Maguire B, Geoghegan KF, Huang A, Rolph T, Liras S, Doudna JA, Dullea RG, Cate JHD. Lintner NG, et al. Among authors: mcclure kf. PLoS Biol. 2018 Apr 17;16(4):e1002628. doi: 10.1371/journal.pbio.1002628. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29664898 Free PMC article.
37 results