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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1936 1
1943 1
1952 1
1954 1
1955 1
1957 2
1958 1
1959 1
1960 1
1961 5
1962 2
1963 3
1964 8
1965 6
1966 9
1967 9
1968 5
1969 6
1970 6
1971 1
1972 4
1973 6
1974 6
1975 9
1976 5
1977 7
1978 4
1979 2
1980 8
1981 10
1982 5
1983 5
1984 9
1985 4
1986 8
1987 8
1988 10
1989 15
1990 12
1991 1
1992 3
1993 6
1994 11
1995 5
1996 7
1997 3
1998 8
1999 8
2000 4
2001 9
2002 7
2003 9
2004 10
2005 11
2006 13
2007 9
2008 14
2009 8
2010 18
2011 23
2012 23
2013 18
2014 12
2015 10
2016 14
2017 16
2018 19
2019 18
2020 19
2021 21
2022 25
2023 1
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Search Results

546 results
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Page 1
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Hofmann MH, Gmachl M, Ramharter J, Savarese F, Gerlach D, Marszalek JR, Sanderson MP, Kessler D, Trapani F, Arnhof H, Rumpel K, Botesteanu DA, Ettmayer P, Gerstberger T, Kofink C, Wunberg T, Zoephel A, Fu SC, Teh JL, Böttcher J, Pototschnig N, Schachinger F, Schipany K, Lieb S, Vellano CP, O'Connell JC, Mendes RL, Moll J, Petronczki M, Heffernan TP, Pearson M, McConnell DB, Kraut N. Hofmann MH, et al. Among authors: mcconnell db. Cancer Discov. 2021 Jan;11(1):142-157. doi: 10.1158/2159-8290.CD-20-0142. Epub 2020 Aug 19. Cancer Discov. 2021. PMID: 32816843 Free PMC article.
Cultural and religious considerations in pediatric palliative care.
Wiener L, McConnell DG, Latella L, Ludi E. Wiener L, et al. Among authors: mcconnell dg. Palliat Support Care. 2013 Feb;11(1):47-67. doi: 10.1017/S1478951511001027. Epub 2012 May 22. Palliat Support Care. 2013. PMID: 22617619 Free PMC article. Review.
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.
Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A. Farnaby W, et al. Among authors: mcconnell db. Nat Chem Biol. 2019 Jul;15(7):672-680. doi: 10.1038/s41589-019-0294-6. Epub 2019 Jun 10. Nat Chem Biol. 2019. PMID: 31178587 Free PMC article.
Drugging an undruggable pocket on KRAS.
Kessler D, Gmachl M, Mantoulidis A, Martin LJ, Zoephel A, Mayer M, Gollner A, Covini D, Fischer S, Gerstberger T, Gmaschitz T, Goodwin C, Greb P, Häring D, Hela W, Hoffmann J, Karolyi-Oezguer J, Knesl P, Kornigg S, Koegl M, Kousek R, Lamarre L, Moser F, Munico-Martinez S, Peinsipp C, Phan J, Rinnenthal J, Sai J, Salamon C, Scherbantin Y, Schipany K, Schnitzer R, Schrenk A, Sharps B, Siszler G, Sun Q, Waterson A, Wolkerstorfer B, Zeeb M, Pearson M, Fesik SW, McConnell DB. Kessler D, et al. Among authors: mcconnell db. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15823-15829. doi: 10.1073/pnas.1904529116. Epub 2019 Jul 22. Proc Natl Acad Sci U S A. 2019. PMID: 31332011 Free PMC article.
Stopping the beating heart of cancer: KRAS reviewed.
Herdeis L, Gerlach D, McConnell DB, Kessler D. Herdeis L, et al. Among authors: mcconnell db. Curr Opin Struct Biol. 2021 Dec;71:136-147. doi: 10.1016/j.sbi.2021.06.013. Epub 2021 Jul 22. Curr Opin Struct Biol. 2021. PMID: 34303932 Free article. Review.
Targeting Son of Sevenless 1: The pacemaker of KRAS.
Kessler D, Gerlach D, Kraut N, McConnell DB. Kessler D, et al. Among authors: mcconnell db. Curr Opin Chem Biol. 2021 Jun;62:109-118. doi: 10.1016/j.cbpa.2021.02.014. Epub 2021 Apr 10. Curr Opin Chem Biol. 2021. PMID: 33848766 Free article. Review.
Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Kerres N, Steurer S, Schlager S, Bader G, Berger H, Caligiuri M, Dank C, Engen JR, Ettmayer P, Fischerauer B, Flotzinger G, Gerlach D, Gerstberger T, Gmaschitz T, Greb P, Han B, Heyes E, Iacob RE, Kessler D, Kölle H, Lamarre L, Lancia DR, Lucas S, Mayer M, Mayr K, Mischerikow N, Mück K, Peinsipp C, Petermann O, Reiser U, Rudolph D, Rumpel K, Salomon C, Scharn D, Schnitzer R, Schrenk A, Schweifer N, Thompson D, Traxler E, Varecka R, Voss T, Weiss-Puxbaum A, Winkler S, Zheng X, Zoephel A, Kraut N, McConnell D, Pearson M, Koegl M. Kerres N, et al. Among authors: mcconnell d. Cell Rep. 2017 Sep 19;20(12):2860-2875. doi: 10.1016/j.celrep.2017.08.081. Cell Rep. 2017. PMID: 28930682 Free article.
Welfarist Psychiatry Goes Global.
McConnell D, Savulescu J. McConnell D, et al. In: Stein D, Singh I, editors. Global Mental Health and Neuroethics. London (UK): Elsevier/Academic Press; 2020 Jan. In: Stein D, Singh I, editors. Global Mental Health and Neuroethics. London (UK): Elsevier/Academic Press; 2020 Jan. PMID: 32721147 Free Books & Documents. Review.
Drugging all RAS isoforms with one pocket.
Kessler D, Bergner A, Böttcher J, Fischer G, Döbel S, Hinkel M, Müllauer B, Weiss-Puxbaum A, McConnell DB. Kessler D, et al. Among authors: mcconnell db. Future Med Chem. 2020 Nov;12(21):1911-1923. doi: 10.4155/fmc-2020-0221. Epub 2020 Aug 11. Future Med Chem. 2020. PMID: 32779487 Free article. Review.
Bone Mineral.
McConnell D. McConnell D. Science. 1964 Sep 18;145(3638):1336. doi: 10.1126/science.145.3638.1336-b. Science. 1964. PMID: 17802018 No abstract available.
546 results