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Local complement activation is associated with primary graft dysfunction after lung transplantation.
Kulkarni HS, Ramphal K, Ma L, Brown M, Oyster M, Speckhart KN, Takahashi T, Byers DE, Porteous MK, Kalman L, Hachem RR, Rushefski M, McPhatter J, Cano M, Kreisel D, Scavuzzo M, Mittler B, Cantu E 3rd, Pilely K, Garred P, Christie JD, Atkinson JP, Gelman AE, Diamond JM. Kulkarni HS, et al. Among authors: mcphatter j. JCI Insight. 2020 Sep 3;5(17):e138358. doi: 10.1172/jci.insight.138358. JCI Insight. 2020. PMID: 32750037 Free PMC article.
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.
Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. Ma L, et al. Among authors: mcphatter j. bioRxiv. 2021 Feb 23:2021.02.22.432177. doi: 10.1101/2021.02.22.432177. Preprint. bioRxiv. 2021. PMID: 33655244 Free PMC article.