Bifidobacterium bifidum enhances hepatic mitochondrial β-oxidation and ameliorates MAFLD in a high-fat diet rat model.
Dashti F, Bolandparvaz A, Panji A, Hojatifar Z, Alinejad M, Mehboodi M, Maleki MH, Mirshekari A, Nadimi E.
Dashti F, et al.
Sci Rep. 2025 Nov 5;15(1):38716. doi: 10.1038/s41598-025-22467-4.
Sci Rep. 2025.
PMID: 41193521
Free PMC article.
This study investigates the role of B. bifidum in modulating hepatic mitochondrial beta-oxidation pathways and key transcriptional regulators involved in fatty acid metabolism. MAFLD was induced in male Sprague-Dawley rats using a high-fat diet and streptozotocin (STZ). .. …
This study investigates the role of B. bifidum in modulating hepatic mitochondrial beta-oxidation pathways and key transcriptional regulator …