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Year Number of Results
2014 1
2017 1
2018 1
2019 1
2020 4
2021 3
2022 0
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10 results
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Page 1
Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D, Yang Q, Wang H, Melick CH, Navlani R, Frank AR, Jewell JL. Meng D, et al. Among authors: melick ch. J Biol Chem. 2020 Mar 6;295(10):2890-2899. doi: 10.1074/jbc.AC119.011578. Epub 2020 Feb 4. J Biol Chem. 2020. PMID: 32019866 Free PMC article.
Regulation of mTORC1 by Upstream Stimuli.
Melick CH, Jewell JL. Melick CH, et al. Genes (Basel). 2020 Aug 25;11(9):989. doi: 10.3390/genes11090989. Genes (Basel). 2020. PMID: 32854217 Free PMC article. Review.
GPCR Signaling and mTORC1 Regulation.
Melick CH, Lama-Sherpa TD, Curukovic A, Jewell JL. Melick CH, et al. Mol Pharmacol. 2021 Dec 28:MOLPHARM-MR-2021-000302. doi: 10.1124/molpharm.121.000302. Online ahead of print. Mol Pharmacol. 2021. PMID: 34965982 Free article.
AKAP13 couples GPCR signaling to mTORC1 inhibition.
Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. Zhang S, et al. Among authors: melick ch. PLoS Genet. 2021 Oct 21;17(10):e1009832. doi: 10.1371/journal.pgen.1009832. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34673774 Free PMC article.
ArfGAP1 inhibits mTORC1 lysosomal localization and activation.
Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. Meng D, et al. Among authors: melick ch. EMBO J. 2021 Jun 15;40(12):e106412. doi: 10.15252/embj.2020106412. Epub 2021 May 14. EMBO J. 2021. PMID: 33988249 Free PMC article.
GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.
Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. Jewell JL, et al. Among authors: melick ch. Elife. 2019 May 21;8:e43038. doi: 10.7554/eLife.43038. Elife. 2019. PMID: 31112131 Free PMC article.