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2013 3
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2017 9
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2020 11
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2022 5
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64 results

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Page 1
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.
Cadby G, Giles C, Melton PE, Huynh K, Mellett NA, Duong T, Nguyen A, Cinel M, Smith A, Olshansky G, Wang T, Brozynska M, Inouye M, McCarthy NS, Ariff A, Hung J, Hui J, Beilby J, Dubé MP, Watts GF, Shah S, Wray NR, Lim WLF, Chatterjee P, Martins I, Laws SM, Porter T, Vacher M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Taddei K, Arnold M, Kastenmüller G, Nho K, Saykin AJ, Han X, Kaddurah-Daouk R, Martins RN, Blangero J, Meikle PJ, Moses EK. Cadby G, et al. Among authors: mellett na. Nat Commun. 2022 Jun 6;13(1):3124. doi: 10.1038/s41467-022-30875-7. Nat Commun. 2022. PMID: 35668104 Free PMC article.
An integrative systems genetic analysis of mammalian lipid metabolism.
Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, Peng KY, Lee R, Jayawardana K, Pan C, Mellett NA, Weir JM, Lazarus R, Lusis AJ, Meikle PJ, James DE, de Aguiar Vallim TQ, Drew BG. Parker BL, et al. Among authors: mellett na. Nature. 2019 Mar;567(7747):187-193. doi: 10.1038/s41586-019-0984-y. Epub 2019 Feb 27. Nature. 2019. PMID: 30814737 Free PMC article.
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU. Braig D, et al. Among authors: mellett na. Nat Commun. 2017 Jan 23;8:14188. doi: 10.1038/ncomms14188. Nat Commun. 2017. PMID: 28112148 Free PMC article.
ABCA12 regulates insulin secretion from β-cells.
Ursino GM, Fu Y, Cottle DL, Mukhamedova N, Jones LK, Low H, Tham MS, Gan WJ, Mellett NA, Das PP, Weir JM, Ditiatkovski M, Fynch S, Thorn P, Thomas HE, Meikle PJ, Parkington HC, Smyth IM, Sviridov D. Ursino GM, et al. Among authors: mellett na. EMBO Rep. 2020 Mar 4;21(3):e48692. doi: 10.15252/embr.201948692. Epub 2020 Feb 18. EMBO Rep. 2020. PMID: 32072744 Free PMC article.
Changes in plasma lipids predict pravastatin efficacy in secondary prevention.
Jayawardana KS, Mundra PA, Giles C, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Marschner IC, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators. Jayawardana KS, et al. Among authors: mellett na. JCI Insight. 2019 Jul 11;4(13):e128438. doi: 10.1172/jci.insight.128438. eCollection 2019 Jul 11. JCI Insight. 2019. PMID: 31292301 Free PMC article. Clinical Trial.
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease.
Huynh K, Lim WLF, Giles C, Jayawardana KS, Salim A, Mellett NA, Smith AAT, Olshansky G, Drew BG, Chatterjee P, Martins I, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Arnold M, Nho K, Saykin AJ, Baillie R, Han X, Kaddurah-Daouk R, Martins RN, Meikle PJ. Huynh K, et al. Among authors: mellett na. Nat Commun. 2020 Nov 10;11(1):5698. doi: 10.1038/s41467-020-19473-7. Nat Commun. 2020. PMID: 33173055 Free PMC article.
APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies.
Wang T, Huynh K, Giles C, Mellett NA, Duong T, Nguyen A, Lim WLF, Smith AA, Olshansky G, Cadby G, Hung J, Hui J, Beilby J, Watts GF, Chatterjee P, Martins I, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Taddei K, Doré V, Fripp J, Arnold M, Kastenmüller G, Nho K, Saykin AJ, Baillie R, Han X, Martins RN, Moses EK, Kaddurah-Daouk R, Meikle PJ. Wang T, et al. Among authors: mellett na. Alzheimers Dement. 2022 Nov;18(11):2151-2166. doi: 10.1002/alz.12538. Epub 2022 Jan 25. Alzheimers Dement. 2022. PMID: 35077012 Free PMC article.
64 results