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Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy.

Wu W, Zhou Q, Masubuchi T, Shi X, Li H, Xu X, Huang M, Meng L, He X, Zhu H, Gao S, Zhang N, Jing R, Sun J, Wang H, Hui E, Wong CC, Xu C. Wu W, et al. Among authors: meng l. Cell. 2020 Aug 20;182(4):855-871.e23. doi: 10.1016/j.cell.2020.07.018. Epub 2020 Jul 29. Cell. 2020. PMID: 32730808

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TREM2 ectodomain and its soluble form in Alzheimer's disease.

Yang J, Fu Z, Zhang X, Xiong M, Meng L, Zhang Z. Yang J, et al. Among authors: meng l. J Neuroinflammation. 2020 Jul 7;17(1):204. doi: 10.1186/s12974-020-01878-2. J Neuroinflammation. 2020. PMID: 32635934 Free PMC article. Review.

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Macrophage, the potential key mediator in CAR-T related CRS.

Hao Z, Li R, Meng L, Han Z, Hong Z. Hao Z, et al. Among authors: meng l. Exp Hematol Oncol. 2020 Jul 10;9:15. doi: 10.1186/s40164-020-00171-5. eCollection 2020. Exp Hematol Oncol. 2020. PMID: 32665874 Free PMC article. Review.

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Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling.

Xu J, Jiang C, Wang X, Geng M, Peng Y, Guo Y, Wang S, Li X, Tao P, Zhang F, Han Y, Ning Q, Zhu W, Meng L, Lu S. Xu J, et al. Among authors: meng l. J Immunol. 2020 Jul 1;205(1):181-192. doi: 10.4049/jimmunol.1901021. Epub 2020 Jun 5. J Immunol. 2020. PMID: 32503893

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Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages.

Zhu W, Lönnblom E, Förster M, Johannesson M, Tao P, Meng L, Lu S, Holmdahl R. Zhu W, et al. Among authors: meng l. Sci Adv. 2020 Oct 21;6(43):eaba9337. doi: 10.1126/sciadv.aba9337. Print 2020 Oct. Sci Adv. 2020. PMID: 33087360 Free PMC article.

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Bioinspired oral delivery of gut microbiota by self-coating with biofilms.

Wang X, Cao Z, Zhang M, Meng L, Ming Z, Liu J. Wang X, et al. Among authors: meng l. Sci Adv. 2020 Jun 24;6(26):eabb1952. doi: 10.1126/sciadv.abb1952. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637620 Free PMC article.

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Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells.

Huang Y, Meng L, Nie Q, Zhou Y, Chen L, Yang S, Fung YME, Li X, Huang C, Cao Y, Li Y, Li X. Huang Y, et al. Among authors: meng l. Nat Chem. 2021 Jan;13(1):77-88. doi: 10.1038/s41557-020-00605-x. Epub 2020 Dec 21. Nat Chem. 2021. PMID: 33349694

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Linc01232 promotes the metastasis of pancreatic cancer by suppressing the ubiquitin-mediated degradation of HNRNPA2B1 and activating the A-Raf-induced MAPK/ERK signaling pathway.

Meng LD, Shi GD, Ge WL, Huang XM, Chen Q, Yuan H, Wu PF, Lu YC, Shen P, Zhang YH, Cao SJ, Miao Y, Tu M, Jiang KR. Meng LD, et al. Cancer Lett. 2020 Dec 1;494:107-120. doi: 10.1016/j.canlet.2020.08.001. Epub 2020 Aug 16. Cancer Lett. 2020. PMID: 32814086

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Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus.

Wang N, Han S, Liu R, Meng L, He H, Zhang Y, Wang C, Lv Y, Wang J, Li X, Ding Y, Fu J, Hou Y, Lu W, Ma W, Zhan Y, Dai B, Zhang J, Pan X, Hu S, Gao J, Jia Q, Zhang L, Ge S, Wang S, Liang P, Hu T, Lu J, Wang X, Zhou H, Ta W, Wang Y, Lu S, He L. Wang N, et al. Among authors: meng l. Phytomedicine. 2020 Dec;79:153333. doi: 10.1016/j.phymed.2020.153333. Epub 2020 Sep 2. Phytomedicine. 2020. PMID: 32920291 Free PMC article.

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Superresolution imaging reveals spatiotemporal propagation of human replication foci mediated by CTCF-organized chromatin structures.

Su QP, Zhao ZW, Meng L, Ding M, Zhang W, Li Y, Liu M, Li R, Gao YQ, Xie XS, Sun Y. Su QP, et al. Among authors: meng l. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15036-15046. doi: 10.1073/pnas.2001521117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541019 Free PMC article.

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