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FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer.
Wang M, Zhang Z, Chen M, Lv Y, Tian S, Meng F, Zhang Y, Guo X, Chen Y, Yang M, Li J, Qiu T, Xu F, Li Z, Zhang Q, Yang J, Sun J, Zhang H, Zhang H, Li H, Wang W. Wang M, et al. Cell Death Dis. 2023 Aug 3;14(8):495. doi: 10.1038/s41419-023-06027-0. Cell Death Dis. 2023. PMID: 37537172 Free PMC article.
1,184 results