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Year Number of Results
1988 1
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1997 3
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1999 3
2000 4
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2002 6
2003 4
2004 1
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2007 2
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2011 6
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2013 4
2014 4
2015 6
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109 results

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Page 1
Alzheimer's-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions.
Szaruga M, Munteanu B, Lismont S, Veugelen S, Horré K, Mercken M, Saido TC, Ryan NS, De Vos T, Savvides SN, Gallardo R, Schymkowitz J, Rousseau F, Fox NC, Hopf C, De Strooper B, Chávez-Gutiérrez L. Szaruga M, et al. Among authors: mercken m. Cell. 2021 Apr 15;184(8):2257-2258. doi: 10.1016/j.cell.2021.03.058. Cell. 2021. PMID: 33861967 Free article. No abstract available.
Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.
Szaruga M, Munteanu B, Lismont S, Veugelen S, Horré K, Mercken M, Saido TC, Ryan NS, De Vos T, Savvides SN, Gallardo R, Schymkowitz J, Rousseau F, Fox NC, Hopf C, De Strooper B, Chávez-Gutiérrez L. Szaruga M, et al. Among authors: mercken m. Cell. 2017 Jul 27;170(3):443-456.e14. doi: 10.1016/j.cell.2017.07.004. Cell. 2017. PMID: 28753424 Free article.
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease.
Janelidze S, Stomrud E, Smith R, Palmqvist S, Mattsson N, Airey DC, Proctor NK, Chai X, Shcherbinin S, Sims JR, Triana-Baltzer G, Theunis C, Slemmon R, Mercken M, Kolb H, Dage JL, Hansson O. Janelidze S, et al. Among authors: mercken m. Nat Commun. 2020 Apr 3;11(1):1683. doi: 10.1038/s41467-020-15436-0. Nat Commun. 2020. PMID: 32246036 Free PMC article.
Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.
Bijttebier S, Theunis C, Jahouh F, Martins DR, Verhemeldonck M, Grauwen K, Dillen L, Mercken M. Bijttebier S, et al. Among authors: mercken m. J Chromatogr A. 2021 Aug 16;1651:462299. doi: 10.1016/j.chroma.2021.462299. Epub 2021 May 28. J Chromatogr A. 2021. PMID: 34107398 Free article.
Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread.
Jang E, Hoxha K, Mozier D, Insana A, Farber E, Changolkar L, Zhang B, Chio TI, Crowe A, Chen R, Mercken M, Lee EB, Luk KC, Brunden KR, Lee VM, Xu H. Jang E, et al. Among authors: mercken m. J Neurosci. 2024 Nov 27;44(48):e0877242024. doi: 10.1523/JNEUROSCI.0877-24.2024. J Neurosci. 2024. PMID: 39500576
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.
Spittaels K, Van den Haute C, Van Dorpe J, Geerts H, Mercken M, Bruynseels K, Lasrado R, Vandezande K, Laenen I, Boon T, Van Lint J, Vandenheede J, Moechars D, Loos R, Van Leuven F. Spittaels K, et al. Among authors: mercken m. J Biol Chem. 2000 Dec 29;275(52):41340-9. doi: 10.1074/jbc.M006219200. J Biol Chem. 2000. PMID: 11007782 Free article.
109 results