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Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.

Wiegman CH, Michaeloudes C, Haji G, Narang P, Clarke CJ, Russell KE, Bao W, Pavlidis S, Barnes PJ, Kanerva J, Bittner A, Rao N, Murphy MP, Kirkham PA, Chung KF, Adcock IM; COPDMAP. Wiegman CH, et al. Among authors: michaeloudes c. J Allergy Clin Immunol. 2015 Sep;136(3):769-80. doi: 10.1016/j.jaci.2015.01.046. Epub 2015 Mar 29. J Allergy Clin Immunol. 2015. PMID: 25828268 Free PMC article.

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Role of Metabolic Reprogramming in Pulmonary Innate Immunity and Its Impact on Lung Diseases.

Michaeloudes C, Bhavsar PK, Mumby S, Xu B, Hui CKM, Chung KF, Adcock IM. Michaeloudes C, et al. J Innate Immun. 2020;12(1):31-46. doi: 10.1159/000504344. Epub 2019 Nov 29. J Innate Immun. 2020. PMID: 31786568 Free PMC article. Review.

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TLR3/TAK1 signalling regulates rhinovirus-induced interleukin-33 in bronchial smooth muscle cells.

Ramu S, Calvén J, Michaeloudes C, Menzel M, Akbarshahi H, Chung KF, Uller L. Ramu S, et al. Among authors: michaeloudes c. ERJ Open Res. 2020 Oct 5;6(4):00147-2020. doi: 10.1183/23120541.00147-2020. eCollection 2020 Oct. ERJ Open Res. 2020. PMID: 33043044 Free PMC article.

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Dealing with Stress: Defective Metabolic Adaptation in Chronic Obstructive Pulmonary Disease Pathogenesis.

Michaeloudes C, Bhavsar PK, Mumby S, Chung KF, Adcock IM. Michaeloudes C, et al. Ann Am Thorac Soc. 2017 Nov;14(Supplement_5):S374-S382. doi: 10.1513/AnnalsATS.201702-153AW. Ann Am Thorac Soc. 2017. PMID: 29161091 Free PMC article. Review.

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Molecular mechanisms of oxidative stress in asthma.

Michaeloudes C, Abubakar-Waziri H, Lakhdar R, Raby K, Dixey P, Adcock IM, Mumby S, Bhavsar PK, Chung KF. Michaeloudes C, et al. Mol Aspects Med. 2022 Jun;85:101026. doi: 10.1016/j.mam.2021.101026. Epub 2021 Oct 6. Mol Aspects Med. 2022. PMID: 34625291 Review.

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Study of Mesenchymal Stem Cell-Mediated Mitochondrial Transfer in In Vitro Models of Oxidant-Mediated Airway Epithelial and Smooth Muscle Cell Injury.

Michaeloudes C, Li X, Mak JCW, Bhavsar PK. Michaeloudes C, et al. Methods Mol Biol. 2021;2269:93-105. doi: 10.1007/978-1-0716-1225-5_7. Methods Mol Biol. 2021. PMID: 33687674

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Metabolic re-patterning in COPD airway smooth muscle cells.

Michaeloudes C, Kuo CH, Haji G, Finch DK, Halayko AJ, Kirkham P, Chung KF, Adcock IM; COPDMAP. Michaeloudes C, et al. Eur Respir J. 2017 Nov 30;50(5):1700202. doi: 10.1183/13993003.00202-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29191950 Free PMC article.

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Effect of silver nanospheres and nanowires on human airway smooth muscle cells: role of sulfidation.

Michaeloudes C, Seiffert J, Chen S, Ruenraroengsak P, Bey L, Theodorou IG, Ryan M, Cui X, Zhang J, Shaffer M, Tetley T, Porter AE, Chung KF. Michaeloudes C, et al. Nanoscale Adv. 2020 Oct 9;2(12):5635-5647. doi: 10.1039/d0na00745e. eCollection 2020 Dec 15. Nanoscale Adv. 2020. PMID: 34381958 Free PMC article.

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DNA methylation modules in airway smooth muscle are associated with asthma severity.

Perry MM, Lavender P, Kuo CS, Galea F, Michaeloudes C, Flanagan JM, Fan Chung K, Adcock IM. Perry MM, et al. Among authors: michaeloudes c. Eur Respir J. 2018 Apr 12;51(4):1701068. doi: 10.1183/13993003.01068-2017. Print 2018 Apr. Eur Respir J. 2018. PMID: 29449426 Free PMC article.

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Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease.

Haji G, Wiegman CH, Michaeloudes C, Patel MS, Curtis K, Bhavsar P, Polkey MI, Adcock IM, Chung KF; COPDMAP consortium. Haji G, et al. Among authors: michaeloudes c. Respir Res. 2020 Oct 12;21(1):262. doi: 10.1186/s12931-020-01527-5. Respir Res. 2020. PMID: 33046036 Free PMC article.

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