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Metabolic regulation of T lymphocytes.

MacIver NJ, Michalek RD, Rathmell JC. MacIver NJ, et al. Among authors: michalek rd. Annu Rev Immunol. 2013;31:259-83. doi: 10.1146/annurev-immunol-032712-095956. Epub 2013 Jan 3. Annu Rev Immunol. 2013. PMID: 23298210 Free PMC article. Review.

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The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

Macintyre AN, Gerriets VA, Nichols AG, Michalek RD, Rudolph MC, Deoliveira D, Anderson SM, Abel ED, Chen BJ, Hale LP, Rathmell JC. Macintyre AN, et al. Among authors: michalek rd. Cell Metab. 2014 Jul 1;20(1):61-72. doi: 10.1016/j.cmet.2014.05.004. Epub 2014 Jun 12. Cell Metab. 2014. PMID: 24930970 Free PMC article.

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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.

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The metabolic life and times of a T-cell.

Michalek RD, Rathmell JC. Michalek RD, et al. Immunol Rev. 2010 Jul;236:190-202. doi: 10.1111/j.1600-065X.2010.00911.x. Immunol Rev. 2010. PMID: 20636818 Free PMC article. Review.

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Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.

Ganguly S, Finkelstein D, Shaw TI, Michalek RD, Zorn KM, Ekins S, Yasuda K, Fukuda Y, Schuetz JD, Mukherjee K, Schuetz EG. Ganguly S, et al. Among authors: michalek rd. PLoS One. 2021 Jul 13;16(7):e0253852. doi: 10.1371/journal.pone.0253852. eCollection 2021. PLoS One. 2021. PMID: 34255797 Free PMC article.

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Methed-up FOXOs can't in-Akt-ivate.

Michalek RD, Rathmell JC. Michalek RD, et al. Mol Cell. 2008 Oct 24;32(2):160-2. doi: 10.1016/j.molcel.2008.10.006. Mol Cell. 2008. PMID: 18951081 Free PMC article.

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Metabolomic profiles and childhood obesity.

Perng W, Gillman MW, Fleisch AF, Michalek RD, Watkins SM, Isganaitis E, Patti ME, Oken E. Perng W, et al. Among authors: michalek rd. Obesity (Silver Spring). 2014 Dec;22(12):2570-8. doi: 10.1002/oby.20901. Epub 2014 Sep 24. Obesity (Silver Spring). 2014. PMID: 25251340 Free PMC article.

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Cigarette smoking is associated with an altered vaginal tract metabolomic profile.

Nelson TM, Borgogna JC, Michalek RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM. Nelson TM, et al. Among authors: michalek rd. Sci Rep. 2018 Jan 16;8(1):852. doi: 10.1038/s41598-017-14943-3. Sci Rep. 2018. PMID: 29339821 Free PMC article.

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Landscape of the mitochondrial Hsp90 metabolome in tumours.

Chae YC, Angelin A, Lisanti S, Kossenkov AV, Speicher KD, Wang H, Powers JF, Tischler AS, Pacak K, Fliedner S, Michalek RD, Karoly ED, Wallace DC, Languino LR, Speicher DW, Altieri DC. Chae YC, et al. Among authors: michalek rd. Nat Commun. 2013;4:2139. doi: 10.1038/ncomms3139. Nat Commun. 2013. PMID: 23842546 Free PMC article.

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Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

Ghosh JC, Siegelin MD, Vaira V, Faversani A, Tavecchio M, Chae YC, Lisanti S, Rampini P, Giroda M, Caino MC, Seo JH, Kossenkov AV, Michalek RD, Schultz DC, Bosari S, Languino LR, Altieri DC. Ghosh JC, et al. Among authors: michalek rd. J Natl Cancer Inst. 2015 Feb 3;107(3):dju502. doi: 10.1093/jnci/dju502. Print 2015 Mar. J Natl Cancer Inst. 2015. PMID: 25650317 Free PMC article.

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