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Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors.
Mol Pharmacol. 2006 Sep;70(3):801-5. doi: 10.1124/mol.106.025130. Epub 2006 Jun 9.
Mol Pharmacol. 2006.
PMID: 16766716
Zinc potentiates neuronal nicotinic receptors by increasing burst duration.
Hsiao B, Mihalak KB, Magleby KL, Luetje CW.
Hsiao B, et al. Among authors: mihalak kb.
J Neurophysiol. 2008 Feb;99(2):999-1007. doi: 10.1152/jn.01040.2007. Epub 2007 Dec 19.
J Neurophysiol. 2008.
PMID: 18094103
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Determinants of zinc potentiation on the alpha4 subunit of neuronal nicotinic receptors.
Hsiao B, Mihalak KB, Repicky SE, Everhart D, Mederos AH, Malhotra A, Luetje CW.
Hsiao B, et al. Among authors: mihalak kb.
Mol Pharmacol. 2006 Jan;69(1):27-36. doi: 10.1124/mol.105.015164. Epub 2005 Sep 27.
Mol Pharmacol. 2006.
PMID: 16189299
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