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Year Number of Results
2014 4
2015 4
2016 2
2017 3
2018 2
2019 3
2020 2
2022 4
2023 4

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26 results

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Page 1
Hallucinating symmetric protein assemblies.
Wicky BIM, Milles LF, Courbet A, Ragotte RJ, Dauparas J, Kinfu E, Tipps S, Kibler RD, Baek M, DiMaio F, Li X, Carter L, Kang A, Nguyen H, Bera AK, Baker D. Wicky BIM, et al. Among authors: milles lf. Science. 2022 Oct 7;378(6615):56-61. doi: 10.1126/science.add1964. Epub 2022 Sep 15. Science. 2022. PMID: 36108048 Free PMC article.
Robust deep learning-based protein sequence design using ProteinMPNN.
Dauparas J, Anishchenko I, Bennett N, Bai H, Ragotte RJ, Milles LF, Wicky BIM, Courbet A, de Haas RJ, Bethel N, Leung PJY, Huddy TF, Pellock S, Tischer D, Chan F, Koepnick B, Nguyen H, Kang A, Sankaran B, Bera AK, King NP, Baker D. Dauparas J, et al. Among authors: milles lf. Science. 2022 Oct 7;378(6615):49-56. doi: 10.1126/science.add2187. Epub 2022 Sep 15. Science. 2022. PMID: 36108050 Free PMC article.
Scaffolding protein functional sites using deep learning.
Wang J, Lisanza S, Juergens D, Tischer D, Watson JL, Castro KM, Ragotte R, Saragovi A, Milles LF, Baek M, Anishchenko I, Yang W, Hicks DR, Expòsit M, Schlichthaerle T, Chun JH, Dauparas J, Bennett N, Wicky BIM, Muenks A, DiMaio F, Correia B, Ovchinnikov S, Baker D. Wang J, et al. Among authors: milles lf. Science. 2022 Jul 22;377(6604):387-394. doi: 10.1126/science.abn2100. Epub 2022 Jul 21. Science. 2022. PMID: 35862514 Free PMC article.
De novo design of protein structure and function with RFdiffusion.
Watson JL, Juergens D, Bennett NR, Trippe BL, Yim J, Eisenach HE, Ahern W, Borst AJ, Ragotte RJ, Milles LF, Wicky BIM, Hanikel N, Pellock SJ, Courbet A, Sheffler W, Wang J, Venkatesh P, Sappington I, Torres SV, Lauko A, De Bortoli V, Mathieu E, Ovchinnikov S, Barzilay R, Jaakkola TS, DiMaio F, Baek M, Baker D. Watson JL, et al. Among authors: milles lf. Nature. 2023 Aug;620(7976):1089-1100. doi: 10.1038/s41586-023-06415-8. Epub 2023 Jul 11. Nature. 2023. PMID: 37433327 Free PMC article.
Extreme mechanical stability in protein complexes.
Milles LF, Gaub HE. Milles LF, et al. Curr Opin Struct Biol. 2020 Feb;60:124-130. doi: 10.1016/j.sbi.2019.11.012. Epub 2020 Feb 10. Curr Opin Struct Biol. 2020. PMID: 32058258 Review.
Calcium stabilizes the strongest protein fold.
Milles LF, Unterauer EM, Nicolaus T, Gaub HE. Milles LF, et al. Nat Commun. 2018 Nov 12;9(1):4764. doi: 10.1038/s41467-018-07145-6. Nat Commun. 2018. PMID: 30420680 Free PMC article.
A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions.
Bauer MS, Gruber S, Hausch A, Gomes PSFC, Milles LF, Nicolaus T, Schendel LC, Navajas PL, Procko E, Lietha D, Melo MCR, Bernardi RC, Gaub HE, Lipfert J. Bauer MS, et al. Among authors: milles lf. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2114397119. doi: 10.1073/pnas.2114397119. Epub 2022 Mar 21. Proc Natl Acad Sci U S A. 2022. PMID: 35312342 Free PMC article.
The free energy landscape of retroviral integration.
Vanderlinden W, Brouns T, Walker PU, Kolbeck PJ, Milles LF, Ott W, Nickels PC, Debyser Z, Lipfert J. Vanderlinden W, et al. Among authors: milles lf. Nat Commun. 2019 Oct 18;10(1):4738. doi: 10.1038/s41467-019-12649-w. Nat Commun. 2019. PMID: 31628321 Free PMC article.
De novo design of knotted tandem repeat proteins.
Doyle LA, Takushi B, Kibler RD, Milles LF, Orozco CT, Jones JD, Jackson SE, Stoddard BL, Bradley P. Doyle LA, et al. Among authors: milles lf. Nat Commun. 2023 Oct 24;14(1):6746. doi: 10.1038/s41467-023-42388-y. Nat Commun. 2023. PMID: 37875492 Free PMC article.
26 results