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Caspase-2 protects against ferroptotic cell death.
Dawar S, Benitez MC, Lim Y, Dite TA, Yousef JM, Thio N, Garciaz S, Jackson TD, Milne JV, Dagley LF, Phillips WA, Kumar S, Clemons NJ. Dawar S, et al. Among authors: milne jv. Cell Death Dis. 2024 Mar 1;15(3):182. doi: 10.1038/s41419-024-06560-6. Cell Death Dis. 2024. PMID: 38429264 Free PMC article.
Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction.
Fujihara KM, Zhang BZ, Jackson TD, Ogunkola MO, Nijagal B, Milne JV, Sallman DA, Ang CS, Nikolic I, Kearney CJ, Hogg SJ, Cabalag CS, Sutton VR, Watt S, Fujihara AT, Trapani JA, Simpson KJ, Stojanovski D, Leimkühler S, Haupt S, Phillips WA, Clemons NJ. Fujihara KM, et al. Among authors: milne jv. Sci Adv. 2022 Sep 16;8(37):eabm9427. doi: 10.1126/sciadv.abm9427. Epub 2022 Sep 14. Sci Adv. 2022. PMID: 36103522 Free PMC article.
Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer.
Cabalag CS, Prall OWJ, Ciciulla J, Galea LA, Thio N, Jayawardana M, Leong TYM, Milne JV, Fujihara KM, Chong L, Hii MW, Arnau GM, Neeson PJ, Phillips WA, Duong CP, Clemons NJ. Cabalag CS, et al. Among authors: milne jv. Ann Surg Oncol. 2023 Mar;30(3):1614-1625. doi: 10.1245/s10434-022-12562-5. Epub 2022 Oct 2. Ann Surg Oncol. 2023. PMID: 36183015 Free PMC article.
Loss of SMAD4 Is Sufficient to Promote Tumorigenesis in a Model of Dysplastic Barrett's Esophagus.
Gotovac JR, Kader T, Milne JV, Fujihara KM, Lara-Gonzalez LE, Gorringe KL, Kalimuthu SN, Jayawardana MW, Duong CP, Phillips WA, Clemons NJ. Gotovac JR, et al. Among authors: milne jv. Cell Mol Gastroenterol Hepatol. 2021;12(2):689-713. doi: 10.1016/j.jcmgh.2021.03.008. Epub 2021 Mar 25. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33774196 Free PMC article.