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Page 1
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma.
Wouters J, Kalender-Atak Z, Minnoye L, Spanier KI, De Waegeneer M, Bravo González-Blas C, Mauduit D, Davie K, Hulselmans G, Najem A, Dewaele M, Pedri D, Rambow F, Makhzami S, Christiaens V, Ceyssens F, Ghanem G, Marine JC, Poovathingal S, Aerts S. Wouters J, et al. Among authors: minnoye l. Nat Cell Biol. 2020 Aug;22(8):986-998. doi: 10.1038/s41556-020-0547-3. Epub 2020 Aug 3. Nat Cell Biol. 2020. PMID: 32753671
Mapping gene regulatory networks from single-cell omics data.
Fiers MWEJ, Minnoye L, Aibar S, Bravo González-Blas C, Kalender Atak Z, Aerts S. Fiers MWEJ, et al. Among authors: minnoye l. Brief Funct Genomics. 2018 Jul 1;17(4):246-254. doi: 10.1093/bfgp/elx046. Brief Funct Genomics. 2018. PMID: 29342231 Free PMC article. Review.
Cross-species analysis of enhancer logic using deep learning.
Minnoye L, Taskiran II, Mauduit D, Fazio M, Van Aerschot L, Hulselmans G, Christiaens V, Makhzami S, Seltenhammer M, Karras P, Primot A, Cadieu E, van Rooijen E, Marine JC, Egidy G, Ghanem GE, Zon L, Wouters J, Aerts S. Minnoye L, et al. Genome Res. 2020 Dec;30(12):1815-1834. doi: 10.1101/gr.260844.120. Epub 2020 Jul 30. Genome Res. 2020. PMID: 32732264 Free PMC article.
cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data.
Bravo González-Blas C, Minnoye L, Papasokrati D, Aibar S, Hulselmans G, Christiaens V, Davie K, Wouters J, Aerts S. Bravo González-Blas C, et al. Among authors: minnoye l. Nat Methods. 2019 May;16(5):397-400. doi: 10.1038/s41592-019-0367-1. Epub 2019 Apr 8. Nat Methods. 2019. PMID: 30962623 Free PMC article.
Analysis of long and short enhancers in melanoma cell states.
Mauduit D, Taskiran II, Minnoye L, de Waegeneer M, Christiaens V, Hulselmans G, Demeulemeester J, Wouters J, Aerts S. Mauduit D, et al. Among authors: minnoye l. Elife. 2021 Dec 7;10:e71735. doi: 10.7554/eLife.71735. Elife. 2021. PMID: 34874265 Free PMC article.
DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance.
D'Anna F, Van Dyck L, Xiong J, Zhao H, Berrens RV, Qian J, Bieniasz-Krzywiec P, Chandra V, Schoonjans L, Matthews J, De Smedt J, Minnoye L, Amorim R, Khorasanizadeh S, Yu Q, Zhao L, De Borre M, Savvides SN, Simon MC, Carmeliet P, Reik W, Rastinejad F, Mazzone M, Thienpont B, Lambrechts D. D'Anna F, et al. Among authors: minnoye l. Genome Biol. 2020 Jul 27;21(1):182. doi: 10.1186/s13059-020-02087-z. Genome Biol. 2020. PMID: 32718321 Free PMC article.