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Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode.

Lucas SCC, Atkinson SJ, Bamborough P, Barnett H, Chung CW, Gordon L, Mitchell DJ, Phillipou A, Prinjha RK, Sheppard RJ, Tomkinson NCO, Watson RJ, Demont EH. Lucas SCC, et al. Among authors: mitchell dj. J Med Chem. 2020 May 28;63(10):5212-5241. doi: 10.1021/acs.jmedchem.0c00021. Epub 2020 May 6. J Med Chem. 2020. PMID: 32321240

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Hierarchical Representation of Multistep Tasks in Multiple-Demand and Default Mode Networks.

Wen T, Duncan J, Mitchell DJ. Wen T, et al. Among authors: mitchell dj. J Neurosci. 2020 Sep 30;40(40):7724-7738. doi: 10.1523/JNEUROSCI.0594-20.2020. Epub 2020 Aug 31. J Neurosci. 2020. PMID: 32868460 Free PMC article.

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GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family.

Preston A, Atkinson SJ, Bamborough P, Chung CW, Gordon LJ, Grandi P, Gray JRJ, Harrison LA, Lewis AJ, Lugo D, Messenger C, Michon AM, Mitchell DJ, Prinjha RK, Rioja I, Seal J, Taylor S, Thesmar P, Wall ID, Watson RJ, Woolven JM, Demont EH. Preston A, et al. Among authors: mitchell dj. ACS Med Chem Lett. 2020 Jul 6;11(8):1581-1587. doi: 10.1021/acsmedchemlett.0c00247. eCollection 2020 Aug 13. ACS Med Chem Lett. 2020. PMID: 32832027

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Experimental translocations to low predation lead to non-parallel increases in relative brain size.

Mitchell DJ, Vega-Trejo R, Kotrschal A. Mitchell DJ, et al. Biol Lett. 2020 Jan;16(1):20190654. doi: 10.1098/rsbl.2019.0654. Epub 2020 Jan 22. Biol Lett. 2020. PMID: 31964256 Free PMC article.

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The time-course of component processes of selective attention.

Wen T, Duncan J, Mitchell DJ. Wen T, et al. Among authors: mitchell dj. Neuroimage. 2019 Oct 1;199:396-407. doi: 10.1016/j.neuroimage.2019.05.067. Epub 2019 May 29. Neuroimage. 2019. PMID: 31150787 Free PMC article.

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Complexity and compositionality in fluid intelligence.

Duncan J, Chylinski D, Mitchell DJ, Bhandari A. Duncan J, et al. Among authors: mitchell dj. Proc Natl Acad Sci U S A. 2017 May 16;114(20):5295-5299. doi: 10.1073/pnas.1621147114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461462 Free PMC article.

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Obituaries:

Mitchell DJ. Mitchell DJ. Br J Radiol. 1975 May;48(569):412. doi: 10.1259/0007-1285-48-569-412-b. Br J Radiol. 1975. PMID: 1095099 No abstract available.

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The Functional Convergence and Heterogeneity of Social, Episodic, and Self-Referential Thought in the Default Mode Network.

Wen T, Mitchell DJ, Duncan J. Wen T, et al. Among authors: mitchell dj. Cereb Cortex. 2020 Oct 1;30(11):5915-5929. doi: 10.1093/cercor/bhaa166. Cereb Cortex. 2020. PMID: 32572493 Free PMC article.

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Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function.

Idris M, Mitchell DJ, Gordon R, Sidharthan NP, Butcher NJ, Minchin RF. Idris M, et al. Among authors: mitchell dj. Drug Metab Dispos. 2020 May;48(5):337-344. doi: 10.1124/dmd.119.089714. Epub 2020 Mar 9. Drug Metab Dispos. 2020. PMID: 32152050

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Design and Synthesis of a Highly Selective and In Vivo-Capable Inhibitor of the Second Bromodomain of the Bromodomain and Extra Terminal Domain Family of Proteins.

Preston A, Atkinson S, Bamborough P, Chung CW, Craggs PD, Gordon L, Grandi P, Gray JRJ, Jones EJ, Lindon M, Michon AM, Mitchell DJ, Prinjha RK, Rianjongdee F, Rioja I, Seal J, Taylor S, Wall I, Watson RJ, Woolven J, Demont EH. Preston A, et al. Among authors: mitchell dj. J Med Chem. 2020 Sep 10;63(17):9070-9092. doi: 10.1021/acs.jmedchem.0c00605. Epub 2020 Aug 20. J Med Chem. 2020. PMID: 32691591

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