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2018 2
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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil A, Nnabuife C, Kearns F, Ye C, Moraes SN, Costacurta F, Esler M, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris R. Moghadasi SA, et al. bioRxiv. 2022 Dec 26:2022.08.07.503099. doi: 10.1101/2022.08.07.503099. Preprint. bioRxiv. 2022. PMID: 35982678 Free PMC article.
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells.
Moghadasi SA, Esler MA, Otsuka Y, Becker JT, Moraes SN, Anderson CB, Chamakuri S, Belica C, Wick C, Harki DA, Young DW, Scampavia L, Spicer TP, Shi K, Aihara H, Brown WL, Harris RS. Moghadasi SA, et al. mBio. 2022 Jun 28;13(3):e0078422. doi: 10.1128/mbio.00784-22. Epub 2022 Apr 26. mBio. 2022. PMID: 35471084 Free PMC article.
Evolution-Guided Structural and Functional Analyses of the HERC Family Reveal an Ancient Marine Origin and Determinants of Antiviral Activity.
Paparisto E, Woods MW, Coleman MD, Moghadasi SA, Kochar DS, Tom SK, Kohio HP, Gibson RM, Rohringer TJ, Hunt NR, Di Gravio EJ, Zhang JY, Tian M, Gao Y, Arts EJ, Barr SD. Paparisto E, et al. Among authors: moghadasi sa. J Virol. 2018 Jun 13;92(13):e00528-18. doi: 10.1128/JVI.00528-18. Print 2018 Jul 1. J Virol. 2018. PMID: 29669830 Free PMC article.
SARS-CoV-2 3CLpro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376.
Heilmann E, Costacurta F, Moghadasi SA, Ye C, Pavan M, Bassani D, Volland A, Ascher C, Weiss AKH, Bante D, Harris RS, Moro S, Rupp B, Martinez-Sobrido L, von Laer D. Heilmann E, et al. Among authors: moghadasi sa. Sci Transl Med. 2023 Jan 11;15(678):eabq7360. doi: 10.1126/scitranslmed.abq7360. Epub 2023 Jan 11. Sci Transl Med. 2023. PMID: 36194133 Free PMC article.
11 results