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Increased transmembrane protein 119 (TMEM119) levels in the cerebrospinal fluid of patients with mild cognitive impairment due to Alzheimer's disease suggest early microglial involvement.
Klassen P, Alexudis C, Klose V, de San José NG, Huss A, Bachhuber F, Soylu Ö, Fazeli B, Erhart D, Laible M, Anderl-Straub S, Jesse S, Otto M, Ludolph AC, Tumani H, Halbgebauer S. Klassen P, et al. Alzheimers Dement (Amst). 2025 Dec 31;18(1):e70240. doi: 10.1002/dad2.70240. eCollection 2026 Jan-Mar. Alzheimers Dement (Amst). 2025. PMID: 41488805 Free PMC article.