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The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6.
Küffer A, Lakkaraju AK, Mogha A, Petersen SC, Airich K, Doucerain C, Marpakwar R, Bakirci P, Senatore A, Monnard A, Schiavi C, Nuvolone M, Grosshans B, Hornemann S, Bassilana F, Monk KR, Aguzzi A. Küffer A, et al. Among authors: monnard a. Nature. 2016 Aug 25;536(7617):464-8. doi: 10.1038/nature19312. Epub 2016 Aug 8. Nature. 2016. PMID: 27501152 Free PMC article.