Moreb E[au] - Search Results

Year	Number of Results
2015	1
2016	1
2017	1
2020	5
2021	4
2022	1

1

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. Nelson CE, et al. Among authors: moreb ea. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. Science. 2016. PMID: 26721684 Free PMC article.

2

Genome dependent Cas9/gRNA search time underlies sequence dependent gRNA activity.

Moreb EA, Lynch MD. Moreb EA, et al. Nat Commun. 2021 Aug 19;12(1):5034. doi: 10.1038/s41467-021-25339-3. Nat Commun. 2021. PMID: 34413309 Free PMC article.

3

CRISPR-Cas "Non-Target" Sites Inhibit On-Target Cutting Rates.

Moreb EA, Hutmacher M, Lynch MD. Moreb EA, et al. CRISPR J. 2020 Dec;3(6):550-561. doi: 10.1089/crispr.2020.0065. CRISPR J. 2020. PMID: 33346713

4

Escherichia coli Cas1/2 Endonuclease Complex Modifies Self-Targeting CRISPR/Cascade Spacers Reducing Silencing Guide Stability.

Ye Z, Moreb EA, Li S, Lebeau J, Menacho-Melgar R, Munson M, Lynch MD. Ye Z, et al. Among authors: moreb ea. ACS Synth Biol. 2021 Jan 15;10(1):29-37. doi: 10.1021/acssynbio.0c00398. Epub 2020 Dec 17. ACS Synth Biol. 2021. PMID: 33331764

5

Dynamic control over feedback regulatory mechanisms improves NADPH flux and xylitol biosynthesis in engineered E. coli.

Li S, Ye Z, Moreb EA, Hennigan JN, Castellanos DB, Yang T, Lynch MD. Li S, et al. Among authors: moreb ea. Metab Eng. 2021 Mar;64:26-40. doi: 10.1016/j.ymben.2021.01.005. Epub 2021 Jan 16. Metab Eng. 2021. PMID: 33460820

6

Scalable, two-stage, autoinduction of recombinant protein expression in E. coli utilizing phosphate depletion.

Menacho-Melgar R, Ye Z, Moreb EA, Yang T, Efromson JP, Decker JS, Wang R, Lynch MD. Menacho-Melgar R, et al. Among authors: moreb ea. Biotechnol Bioeng. 2020 Sep;117(9):2715-2727. doi: 10.1002/bit.27440. Epub 2020 Jun 10. Biotechnol Bioeng. 2020. PMID: 32441815

7

Media Robustness and Scalability of Phosphate Regulated Promoters Useful for Two-Stage Autoinduction in E. coli.

Moreb EA, Ye Z, Efromson JP, Hennigan JN, Menacho-Melgar R, Lynch MD. Moreb EA, et al. ACS Synth Biol. 2020 Jun 19;9(6):1483-1486. doi: 10.1021/acssynbio.0c00182. Epub 2020 May 27. ACS Synth Biol. 2020. PMID: 32353228

8

Two-stage dynamic deregulation of metabolism improves process robustness & scalability in engineered E. coli.

Ye Z, Li S, Hennigan JN, Lebeau J, Moreb EA, Wolf J, Lynch MD. Ye Z, et al. Among authors: moreb ea. Metab Eng. 2021 Nov;68:106-118. doi: 10.1016/j.ymben.2021.09.009. Epub 2021 Sep 30. Metab Eng. 2021. PMID: 34600151

9

Improved two-stage protein expression and purification via autoinduction of both autolysis and auto DNA/RNA hydrolysis conferred by phage lysozyme and DNA/RNA endonuclease.

Menacho-Melgar R, Moreb EA, Efromson JP, Yang T, Hennigan JN, Wang R, Lynch MD. Menacho-Melgar R, et al. Among authors: moreb ea. Biotechnol Bioeng. 2020 Sep;117(9):2852-2860. doi: 10.1002/bit.27444. Epub 2020 Jun 20. Biotechnol Bioeng. 2020. PMID: 32462658

10

Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity.

Moreb EA, Hoover B, Yaseen A, Valyasevi N, Roecker Z, Menacho-Melgar R, Lynch MD. Moreb EA, et al. ACS Synth Biol. 2017 Dec 15;6(12):2209-2218. doi: 10.1021/acssynbio.7b00174. Epub 2017 Oct 2. ACS Synth Biol. 2017. PMID: 28915012

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