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Class I histone deacetylases (HDAC1-3) are histone lysine delactylases.
Moreno-Yruela C, Zhang D, Wei W, Bæk M, Liu W, Gao J, Danková D, Nielsen AL, Bolding JE, Yang L, Jameson ST, Wong J, Olsen CA, Zhao Y. Moreno-Yruela C, et al. Sci Adv. 2022 Jan 21;8(3):eabi6696. doi: 10.1126/sciadv.abi6696. Epub 2022 Jan 19. Sci Adv. 2022. PMID: 35044827 Free PMC article.
Lysine L-lactylation is the dominant lactylation isomer induced by glycolysis.
Zhang D, Gao J, Zhu Z, Mao Q, Xu Z, Singh PK, Rimayi CC, Moreno-Yruela C, Xu S, Li G, Sin YC, Chen Y, Olsen CA, Snyder NW, Dai L, Li L, Zhao Y. Zhang D, et al. Among authors: moreno yruela c. Nat Chem Biol. 2024 Jul 19. doi: 10.1038/s41589-024-01680-8. Online ahead of print. Nat Chem Biol. 2024. PMID: 39030363
Histone Deacetylase 11 Is an ε-N-Myristoyllysine Hydrolase.
Moreno-Yruela C, Galleano I, Madsen AS, Olsen CA. Moreno-Yruela C, et al. Cell Chem Biol. 2018 Jul 19;25(7):849-856.e8. doi: 10.1016/j.chembiol.2018.04.007. Epub 2018 May 3. Cell Chem Biol. 2018. PMID: 29731425 Free article.
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