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92 results

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Page 1
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers.
Wong DP, Roy NK, Zhang K, Anukanth A, Asthana A, Shirkey-Son NJ, Dunmire S, Jones BJ, Lahr WS, Webber BR, Moriarity BS, Caimi P, Parameswaran R. Wong DP, et al. Among authors: moriarity bs. Nat Commun. 2022 Jan 11;13(1):217. doi: 10.1038/s41467-021-27853-w. Nat Commun. 2022. PMID: 35017485 Free PMC article.
Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV.
Naeimi Kararoudi M, Likhite S, Elmas E, Yamamoto K, Schwartz M, Sorathia K, de Souza Fernandes Pereira M, Sezgin Y, Devine RD, Lyberger JM, Behbehani GK, Chakravarti N, Moriarity BS, Meyer K, Lee DA. Naeimi Kararoudi M, et al. Among authors: moriarity bs. Cell Rep Methods. 2022 Jun 13;2(6):100236. doi: 10.1016/j.crmeth.2022.100236. eCollection 2022 Jun 20. Cell Rep Methods. 2022. PMID: 35784645 Free PMC article.
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair.
Webber BR, Johnson MJ, Skeate JG, Slipek NJ, Lahr WS, DeFeo AP, Mills LJ, Qiu X, Rathmann B, Diers MD, Wick B, Henley T, Choudhry M, Starr TK, McIvor RS, Moriarity BS. Webber BR, et al. Among authors: moriarity bs. Nat Biomed Eng. 2023 Dec 13:10.1038/s41551-023-01157-4. doi: 10.1038/s41551-023-01157-4. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38092857
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: moriarity bs. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
The Molecular Imaging of Natural Killer Cells.
Shapovalova M, Pyper SR, Moriarity BS, LeBeau AM. Shapovalova M, et al. Among authors: moriarity bs. Mol Imaging. 2018 Jan-Dec;17:1536012118794816. doi: 10.1177/1536012118794816. Mol Imaging. 2018. PMID: 30203710 Free PMC article. Review.
Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing.
Wang M, Krueger JB, Gilkey AK, Stelljes EM, Kluesner MG, Pomeroy EJ, Skeate JG, Slipek NJ, Lahr WS, Vázquez PNC, Zhao Y, Eaton EJ, Laoharawee K, Webber BR, Moriarity BS. Wang M, et al. Among authors: moriarity bs. bioRxiv [Preprint]. 2024 Mar 8:2024.03.05.582637. doi: 10.1101/2024.03.05.582637. bioRxiv. 2024. PMID: 38496503 Free PMC article. Preprint.
Nonviral genome engineering of natural killer cells.
Robbins GM, Wang M, Pomeroy EJ, Moriarity BS. Robbins GM, et al. Among authors: moriarity bs. Stem Cell Res Ther. 2021 Jun 16;12(1):350. doi: 10.1186/s13287-021-02406-6. Stem Cell Res Ther. 2021. PMID: 34134774 Free PMC article. Review.
Primary B cell engineering for therapeutic research.
Kleinboehl E, Laoharawee K, Moriarity BS. Kleinboehl E, et al. Among authors: moriarity bs. Trends Mol Med. 2022 Jun;28(6):528-529. doi: 10.1016/j.molmed.2022.03.007. Epub 2022 Apr 13. Trends Mol Med. 2022. PMID: 35430120 Free PMC article. No abstract available.
CRISPR-Cas9 base editors and their current role in human therapeutics.
Lahr WS, Sipe CJ, Skeate JG, Webber BR, Moriarity BS. Lahr WS, et al. Among authors: moriarity bs. Cytotherapy. 2023 Mar;25(3):270-276. doi: 10.1016/j.jcyt.2022.11.013. Epub 2023 Jan 10. Cytotherapy. 2023. PMID: 36635153 Free PMC article. Review.
92 results