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Modulating Mitophagy in Mitochondrial Disease.

Dombi E, Mortiboys H, Poulton J. Dombi E, et al. Among authors: mortiboys h. Curr Med Chem. 2018;25(40):5597-5612. doi: 10.2174/0929867324666170616101741. Curr Med Chem. 2018. PMID: 28618992 Free article. Review.

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Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically?

Macdonald R, Barnes K, Hastings C, Mortiboys H. Macdonald R, et al. Among authors: mortiboys h. Biochem Soc Trans. 2018 Aug 20;46(4):891-909. doi: 10.1042/BST20170501. Epub 2018 Jul 19. Biochem Soc Trans. 2018. PMID: 30026371 Free article. Review.

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Mitochondrial Dysfunction in Alzheimer's Disease: A Biomarker of the Future?

Bell SM, Barnes K, De Marco M, Shaw PJ, Ferraiuolo L, Blackburn DJ, Venneri A, Mortiboys H. Bell SM, et al. Among authors: mortiboys h. Biomedicines. 2021 Jan 11;9(1):63. doi: 10.3390/biomedicines9010063. Biomedicines. 2021. PMID: 33440662 Free PMC article. Review.

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Peripheral Glycolysis in Neurodegenerative Diseases.

Bell SM, Burgess T, Lee J, Blackburn DJ, Allen SP, Mortiboys H. Bell SM, et al. Among authors: mortiboys h. Int J Mol Sci. 2020 Nov 24;21(23):8924. doi: 10.3390/ijms21238924. Int J Mol Sci. 2020. PMID: 33255513 Free PMC article. Review.

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Screening for chemical modulators for LRRK2.

Mortiboys H. Mortiboys H. Biochem Soc Trans. 2016 Dec 15;44(6):1617-1623. doi: 10.1042/BST20160242. Biochem Soc Trans. 2016. PMID: 27913670 Free article. Review.

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Translational approaches to restoring mitochondrial function in Parkinson's disease.

Mortiboys H, Macdonald R, Payne T, Sassani M, Jenkins T, Bandmann O. Mortiboys H, et al. FEBS Lett. 2018 Mar;592(5):776-792. doi: 10.1002/1873-3468.12920. Epub 2017 Dec 17. FEBS Lett. 2018. PMID: 29178330 Free article. Review.

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The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity.

Frison M, Faccenda D, Abeti R, Rigon M, Strobbe D, England-Rendon BS, Cash D, Barnes K, Sadeghian M, Sajic M, Wells LA, Xia D, Giunti P, Smith K, Mortiboys H, Turkheimer FE, Campanella M. Frison M, et al. Among authors: mortiboys h. Mol Psychiatry. 2021 Jul;26(7):2721-2739. doi: 10.1038/s41380-021-01050-z. Epub 2021 Mar 4. Mol Psychiatry. 2021. PMID: 33664474 Free PMC article.

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Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis.

Sassani M, Alix JJ, McDermott CJ, Baster K, Hoggard N, Wild JM, Mortiboys HJ, Shaw PJ, Wilkinson ID, Jenkins TM. Sassani M, et al. Among authors: mortiboys hj. Brain. 2020 Dec 1;143(12):3603-3618. doi: 10.1093/brain/awaa340. Brain. 2020. PMID: 33439988

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A Parkinson's Disease-relevant Mitochondrial and Neuronal Morphology High-throughput Screening Assay in LUHMES Cells.

Leah T, Vazquez-Villaseñor I, Ferraiuolo L, Wharton SB, Mortiboys H. Leah T, et al. Among authors: mortiboys h. Bio Protoc. 2021 Jan 5;11(1):e3881. doi: 10.21769/BioProtoc.3881. eCollection 2021 Jan 5. Bio Protoc. 2021. PMID: 33732769 Free PMC article.

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Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function.

Vazquez-Villasenor I, Garwood CJ, Simpson JE, Heath PR, Mortiboys H, Wharton SB. Vazquez-Villasenor I, et al. Among authors: mortiboys h. Eur J Neurosci. 2021 Nov;54(9):6987-7005. doi: 10.1111/ejn.15466. Epub 2021 Oct 7. Eur J Neurosci. 2021. PMID: 34536321 Free article.

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