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901 results

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Page 1
MTRR rs1532268 polymorphism and gastric cancer risk: evidence from a meta-analysis.
Zhong G, Luo X, Li J, Liao Y, Gui G, Sheng J. Zhong G, et al. J Int Med Res. 2022 May;50(5):3000605221097486. doi: 10.1177/03000605221097486. J Int Med Res. 2022. PMID: 35579185 Free PMC article.
OBJECTIVE: The methionine synthase reductase (MTRR) gene encodes the MTRR enzyme involved in the metabolic pathway of homocysteine. ...CONCLUSION: Our meta-analysis suggests a positive correlation between MTRR rs1532268 polymorphism and GC development....
OBJECTIVE: The methionine synthase reductase (MTRR) gene encodes the MTRR enzyme involved in the metabolic pathway of homocyst …
A meta-analysis of MTRR A66G polymorphism and colorectal cancer susceptibility.
Wu PP, Tang RN, An L. Wu PP, et al. J BUON. 2015 May-Jun;20(3):918-22. J BUON. 2015. PMID: 26214647 Free article. Review.
PURPOSE: A meta-analysis was performed to determine the association between MTRR A66G polymorphism and colorectal cancer (CRC) susceptibility. METHODS: Based on comprehensive searches of the MEDLINE, EMBASE and ISI Web of knowledge, China National Knowledge Infrastructure …
PURPOSE: A meta-analysis was performed to determine the association between MTRR A66G polymorphism and colorectal cancer (CRC) suscep …
Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice.
Sowton AP, Padmanabhan N, Tunster SJ, McNally BD, Murgia A, Yusuf A, Griffin JL, Murray AJ, Watson ED. Sowton AP, et al. Mol Genet Metab Rep. 2020 Mar 24;23:100580. doi: 10.1016/j.ymgmr.2020.100580. eCollection 2020 Jun. Mol Genet Metab Rep. 2020. PMID: 32257815 Free PMC article.
To improve our understanding of this link, we investigated liver morphology, metabolism and fuel storage in adult mice with a hypomorphic mutation in the gene methionine synthase reductase (Mtrr (gt) ). MTRR enzyme is a key regulator of the methionine and folate cyc …
To improve our understanding of this link, we investigated liver morphology, metabolism and fuel storage in adult mice with a hypomorphic mu …
The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival.
Wang Y, Du M, Vallis J, Shariati M, Parfrey PS, Mclaughlin JR, Wang PP, Zhu Y. Wang Y, et al. Nutrients. 2022 Nov 1;14(21):4594. doi: 10.3390/nu14214594. Nutrients. 2022. PMID: 36364857 Free PMC article.
RESULTS: The MTRR and MTHFR genes were associated with DFS and CRC-specific survival in CRC patients at the gene level. After multiple comparison adjustment, MTRR rs1801394 A (vs. G) allele was associated with increased DFS (p = 0.024), while MTHRT rs3737966 (G vs. …
RESULTS: The MTRR and MTHFR genes were associated with DFS and CRC-specific survival in CRC patients at the gene level. After multipl …
MtrR modulates rpoH expression and levels of antimicrobial resistance in Neisseria gonorrhoeae.
Folster JP, Johnson PJ, Jackson L, Dhulipali V, Dyer DW, Shafer WM. Folster JP, et al. J Bacteriol. 2009 Jan;191(1):287-97. doi: 10.1128/JB.01165-08. Epub 2008 Oct 31. J Bacteriol. 2009. PMID: 18978065 Free PMC article.
In order to determine whether MtrR can exert regulatory action on other gonococcal genes, we performed a whole-genome microarray analysis using total RNA extracted from actively growing broth cultures of isogenic MtrR-positive and MtrR-negative gonococci. ... …
In order to determine whether MtrR can exert regulatory action on other gonococcal genes, we performed a whole-genome microarray anal …
MTR, MTRR and CBS Gene Polymorphisms in Recurrent Miscarriages: A Case Control Study from North India.
Talwar S, Prasad S, Kaur L, Mishra J, Puri M, Sachdeva MP, Saraswathy KN. Talwar S, et al. J Hum Reprod Sci. 2022 Apr-Jun;15(2):191-196. doi: 10.4103/jhrs.jhrs_186_21. Epub 2022 Jun 30. J Hum Reprod Sci. 2022. PMID: 35928461 Free PMC article.
RESULTS: MTR A2756G genetic polymorphism was not associated with the risk of RM. The ancestral allele of MTRR A66G and the mutant allele of CBS 844INS68 was causing an increased risk of more than two folds for RM. ...CONCLUSION: Genetic polymorphisms particularly MTRR …
RESULTS: MTR A2756G genetic polymorphism was not associated with the risk of RM. The ancestral allele of MTRR A66G and the mutant all …
What's the Mtrr with your grandparents?
Greer EL, Shi Y. Greer EL, et al. Cell Metab. 2013 Oct 1;18(4):457-9. doi: 10.1016/j.cmet.2013.09.016. Cell Metab. 2013. PMID: 24093670 Free PMC article.
Padmanabhan et al. (2013) show that mutation in mice of a folate metabolism gene, Mtrr, which encodes for methionine synthase reductase, causes developmental defects not only in the mutant progeny, but also in genetically wild-type descendants for up to four generations... …
Padmanabhan et al. (2013) show that mutation in mice of a folate metabolism gene, Mtrr, which encodes for methionine synthase reducta …
MTHFR and MTRR Genetic Polymorphism of Methotrexate Therapy Outcomes in Early Rheumatoid Arthritis.
Zhang Q, Fu P, Cao Z, Huang H, Wen Q, Wang K, Kong T, Wu X, Zheng J. Zhang Q, et al. Pharmgenomics Pers Med. 2023 May 2;16:407-423. doi: 10.2147/PGPM.S404949. eCollection 2023. Pharmgenomics Pers Med. 2023. PMID: 37159804 Free PMC article.
Genotyping of patients MTHFR C677T and A1298C, MTRR A66G using tetra-primer ARMS-PCR method and sanger sequencing to verify its accuracy. ...CONCLUSION: Our findings suggest that the MTHFR C677T, MTHFR A1298C and MTRR A66G polymorphisms may not predict MTX clinical …
Genotyping of patients MTHFR C677T and A1298C, MTRR A66G using tetra-primer ARMS-PCR method and sanger sequencing to verify its accur …
Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Beggs GA, Ayala JC, Kavanaugh LG, Read TD, Hooks GM, Schumacher MA, Shafer WM, Brennan RG. Beggs GA, et al. Nucleic Acids Res. 2021 Apr 19;49(7):4155-4170. doi: 10.1093/nar/gkab213. Nucleic Acids Res. 2021. PMID: 33784401 Free PMC article.
However, the DNA-recognition mechanism of MtrR and the consensus sequence within these operators to which MtrR binds has remained unknown. ...We complement our structural data with a comprehensive mutational analysis of key MtrR-DNA contacts to reveal their i …
However, the DNA-recognition mechanism of MtrR and the consensus sequence within these operators to which MtrR binds has remai …
Riboflavin intake, MTRR genetic polymorphism (rs1532268) and gastric cancer risk in a Korean population: a case-control study.
Lu YT, Gunathilake M, Lee J, Choi IJ, Kim YI, Kim J. Lu YT, et al. Br J Nutr. 2022 Apr 14;127(7):1026-1033. doi: 10.1017/S0007114521001811. Epub 2021 Jun 3. Br J Nutr. 2022. PMID: 34078503
We carried out a study examining the association of riboflavin intake and its interaction with MTRR (rs1532268) genetic variants with GC risk among 756 controls and 377 cases. The OR and 95 % CI were evaluated using unconditional logistic regression models. We observed pro …
We carried out a study examining the association of riboflavin intake and its interaction with MTRR (rs1532268) genetic variants with …
901 results