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Page 1
A compendium of mutational cancer driver genes.
Martínez-Jiménez F, Muiños F, Sentís I, Deu-Pons J, Reyes-Salazar I, Arnedo-Pac C, Mularoni L, Pich O, Bonet J, Kranas H, Gonzalez-Perez A, Lopez-Bigas N. Martínez-Jiménez F, et al. Among authors: muinos f. Nat Rev Cancer. 2020 Oct;20(10):555-572. doi: 10.1038/s41568-020-0290-x. Epub 2020 Aug 10. Nat Rev Cancer. 2020. PMID: 32778778 Review.
Five latent factors underlie response to immunotherapy.
Usset J, Rosendahl Huber A, Andrianova MA, Batlle E, Carles J, Cuppen E, Elez E, Felip E, Gómez-Rey M, Lo Giacco D, Martinez-Jimenez F, Muñoz-Couselo E, Siu LL, Tabernero J, Vivancos A, Muiños F, Gonzalez-Perez A, Lopez-Bigas N. Usset J, et al. Among authors: muinos f. Nat Genet. 2024 Oct;56(10):2112-2120. doi: 10.1038/s41588-024-01899-0. Epub 2024 Sep 12. Nat Genet. 2024. PMID: 39266764 Free PMC article.
Hotspot propensity across mutational processes.
Arnedo-Pac C, Muiños F, Gonzalez-Perez A, Lopez-Bigas N. Arnedo-Pac C, et al. Among authors: muinos f. Mol Syst Biol. 2024 Jan;20(1):6-27. doi: 10.1038/s44320-023-00001-w. Epub 2023 Dec 20. Mol Syst Biol. 2024. PMID: 38177930 Free PMC article.
The mutational footprints of cancer therapies.
Pich O, Muiños F, Lolkema MP, Steeghs N, Gonzalez-Perez A, Lopez-Bigas N. Pich O, et al. Among authors: muinos f. Nat Genet. 2019 Dec;51(12):1732-1740. doi: 10.1038/s41588-019-0525-5. Epub 2019 Nov 18. Nat Genet. 2019. PMID: 31740835 Free PMC article.
In silico saturation mutagenesis of cancer genes.
Muiños F, Martínez-Jiménez F, Pich O, Gonzalez-Perez A, Lopez-Bigas N. Muiños F, et al. Nature. 2021 Aug;596(7872):428-432. doi: 10.1038/s41586-021-03771-1. Epub 2021 Jul 28. Nature. 2021. PMID: 34321661
The evolution of hematopoietic cells under cancer therapy.
Pich O, Cortes-Bullich A, Muiños F, Pratcorona M, Gonzalez-Perez A, Lopez-Bigas N. Pich O, et al. Among authors: muinos f. Nat Commun. 2021 Aug 10;12(1):4803. doi: 10.1038/s41467-021-24858-3. Nat Commun. 2021. PMID: 34376657 Free PMC article.
Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis.
Demajo S, Ramis-Zaldivar JE, Muiños F, Grau ML, Andrianova M, López-Bigas N, González-Pérez A. Demajo S, et al. Among authors: muinos f. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299893. doi: 10.1101/2023.12.13.23299893. medRxiv. 2023. Update in: Cancer Discov. 2024 Sep 4;14(9):1717-1731. doi: 10.1158/2159-8290.CD-23-1416. PMID: 38168256 Free PMC article. Updated. Preprint.
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