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46 results

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Page 1
Nucleic acid detection with CRISPR-Cas13a/C2c2.
Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F. Gootenberg JS, et al. Among authors: myhrvold c. Science. 2017 Apr 28;356(6336):438-442. doi: 10.1126/science.aam9321. Epub 2017 Apr 13. Science. 2017. PMID: 28408723 Free PMC article.
Field-deployable viral diagnostics using CRISPR-Cas13.
Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I, Gehrke L, Zhang F, Sabeti PC. Myhrvold C, et al. Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836. Science. 2018. PMID: 29700266 Free PMC article.
Massively multiplexed nucleic acid detection with Cas13.
Ackerman CM, Myhrvold C, Thakku SG, Freije CA, Metsky HC, Yang DK, Ye SH, Boehm CK, Kosoko-Thoroddsen TF, Kehe J, Nguyen TG, Carter A, Kulesa A, Barnes JR, Dugan VG, Hung DT, Blainey PC, Sabeti PC. Ackerman CM, et al. Among authors: myhrvold c. Nature. 2020 Jun;582(7811):277-282. doi: 10.1038/s41586-020-2279-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32349121 Free PMC article.
Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing.
Nguyen LT, Rakestraw NR, Pizzano BLM, Young CB, Huang Y, Beerensson KT, Fang A, Antal SG, Anamisis KV, Peggs CMD, Yan J, Jing Y, Burdine RD, Adamson B, Toettcher JE, Myhrvold C, Jain PK. Nguyen LT, et al. Among authors: myhrvold c. bioRxiv [Preprint]. 2024 Jul 10:2024.07.09.602710. doi: 10.1101/2024.07.09.602710. bioRxiv. 2024. PMID: 39026836 Free PMC article. Preprint.
Designing sensitive viral diagnostics with machine learning.
Metsky HC, Welch NL, Pillai PP, Haradhvala NJ, Rumker L, Mantena S, Zhang YB, Yang DK, Ackerman CM, Weller J, Blainey PC, Myhrvold C, Mitzenmacher M, Sabeti PC. Metsky HC, et al. Among authors: myhrvold c. Nat Biotechnol. 2022 Jul;40(7):1123-1131. doi: 10.1038/s41587-022-01213-5. Epub 2022 Mar 3. Nat Biotechnol. 2022. PMID: 35241837 Free PMC article.
Highly multiplexed mRNA quantitation with CRISPR-Cas13.
Kang B, Zhang J, Schwoerer MP, Nelson AN, Schoeman E, Guo A, Ploss A, Myhrvold C. Kang B, et al. Among authors: myhrvold c. bioRxiv [Preprint]. 2023 Sep 6:2023.08.16.553527. doi: 10.1101/2023.08.16.553527. bioRxiv. 2023. PMID: 37645785 Free PMC article. Preprint.
What are the current bottlenecks in developing and applying CRISPR technologies?
Kellogg EH, Gootenberg J, Abudayyeh O, Wong ASL, Dahlman JE, Lapinaite A, Myhrvold C, Liu CC, Hsu PD, Mali P, Qi LS. Kellogg EH, et al. Among authors: myhrvold c. Cell Syst. 2022 Aug 17;13(8):589-593. doi: 10.1016/j.cels.2022.07.004. Cell Syst. 2022. PMID: 35981511 Free article. No abstract available.
Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants.
Welch NL, Zhu M, Hua C, Weller J, Mirhashemi ME, Nguyen TG, Mantena S, Bauer MR, Shaw BM, Ackerman CM, Thakku SG, Tse MW, Kehe J, Uwera MM, Eversley JS, Bielwaski DA, McGrath G, Braidt J, Johnson J, Cerrato F, Moreno GK, Krasilnikova LA, Petros BA, Gionet GL, King E, Huard RC, Jalbert SK, Cleary ML, Fitzgerald NA, Gabriel SB, Gallagher GR, Smole SC, Madoff LC, Brown CM, Keller MW, Wilson MM, Kirby MK, Barnes JR, Park DJ, Siddle KJ, Happi CT, Hung DT, Springer M, MacInnis BL, Lemieux JE, Rosenberg E, Branda JA, Blainey PC, Sabeti PC, Myhrvold C. Welch NL, et al. Among authors: myhrvold c. Nat Med. 2024 Jan;30(1):307. doi: 10.1038/s41591-023-02684-y. Nat Med. 2024. PMID: 37946059 Free PMC article. No abstract available.
46 results