Therapeutic efficacy of 166Holmium siloxane in microbrachytherapy of induced glioblastoma in minipig tumor model.
Khoshnevis M, Brown R, Belluco S, Zahi I, Maciocco L, Bonnefont-Rebeix C, Pillet-Michelland E, Tranel J, Roger T, Nennig C, Oudoire P, Marcon L, Tillement O, Louis C, Gehan H, Bardiès M, Mariani M, Muzio V, Meunier JP, Duchemin C, Michel N, N'Tsiba E, Haddad F, Buronfosse T, Carozzo C, Ponce F.
Khoshnevis M, et al.
Front Oncol. 2022 Nov 7;12:923679. doi: 10.3389/fonc.2022.923679. eCollection 2022.
Front Oncol. 2022.
PMID: 36419904
Free PMC article.
Minipigs had injections into the tumor, containing microparticle suspensions of either (166)Ho (group 1; n = 6) or (165)Ho (group 2; n = 3) and control group (group 3; n = 3). The survival time from treatment to euthanasia was 66 days with a good state of hea …
Minipigs had injections into the tumor, containing microparticle suspensions of either (166)Ho (group 1; n = 6) or (165)Ho (group 2; …