Pretargeted PET of Osteodestructive Lesions in Dogs.
Maitz CA, Delaney S, Cook BE, Genady AR, Hoerres R, Kuchuk M, Makris G, Valliant JF, Sadeghi S, Lewis JS, Hennkens HM, Bryan JN, Zeglis BM.
Maitz CA, et al.
Mol Pharm. 2022 Sep 5;19(9):3153-3162. doi: 10.1021/acs.molpharmaceut.2c00220. Epub 2022 May 30.
Mol Pharm. 2022.
PMID: 35635337
Free PMC article.
PET images were collected 1, 6, and 24 h after the administration of [(64)Cu]Cu-SarAr-Tz, revealing that this approach produced high activity concentrations in the bone (>20 and >15%ID/g in the femur and humerus, respectively, at 24 h post injection) as well as high target- …
PET images were collected 1, 6, and 24 h after the administration of [(64)Cu]Cu-SarAr-Tz, revealing that this approach produced high activit …