Influence of shear stress magnitude and direction on atherosclerotic plaque composition.
Pedrigi RM, Mehta VV, Bovens SM, Mohri Z, Poulsen CB, Gsell W, Tremoleda JL, Towhidi L, de Silva R, Petretto E, Krams R.
Pedrigi RM, et al.
R Soc Open Sci. 2016 Oct 19;3(10):160588. doi: 10.1098/rsos.160588. eCollection 2016 Oct.
R Soc Open Sci. 2016.
PMID: 27853578
Free PMC article.
Herein, we sought to test the hypothesis that changes in flow magnitude promote formation of the upstream (vulnerable) plaque, whereas altered flow direction is important for development of the downstream (stable) plaque. We instrumented ApoE(-/-) mice (n = 7) with a cuff …
Herein, we sought to test the hypothesis that changes in flow magnitude promote formation of the upstream (vulnerable) plaque, whereas alter …