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A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase.
Ragavan VN, Nair PC, Jarzebska N, Angom RS, Ruta L, Bianconi E, Grottelli S, Tararova ND, Ryazanskiy D, Lentz SR, Tommasi S, Martens-Lobenhoffer J, Suzuki-Yamamoto T, Kimoto M, Rubets E, Chau S, Chen Y, Hu X, Bernhardt N, Spieth PM, Weiss N, Bornstein SR, Mukhopadhyay D, Bode-Böger SM, Maas R, Wang Y, Macchiarulo A, Mangoni AA, Cellini B, Rodionov RN. Ragavan VN, et al. Among authors: nair pc. Nat Commun. 2023 Jun 9;14(1):3392. doi: 10.1038/s41467-023-38467-9. Nat Commun. 2023. PMID: 37296100 Free PMC article.
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
Nair PC, Chau N, McKinnon RA, Miners JO. Nair PC, et al. Mol Pharmacol. 2020 Dec;98(6):710-718. doi: 10.1124/molpharm.120.000104. Epub 2020 Oct 2. Mol Pharmacol. 2020. PMID: 33008919
Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulating the nitric oxide pathway.
Doman AJ, Tommasi S, Perkins MV, McKinnon RA, Mangoni AA, Nair PC. Doman AJ, et al. Among authors: nair pc. Bioorg Med Chem. 2022 Oct 15;72:116970. doi: 10.1016/j.bmc.2022.116970. Epub 2022 Aug 27. Bioorg Med Chem. 2022. PMID: 36063653 Review.
52 results