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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 1
2007 1
2009 3
2010 1
2011 2
2012 8
2013 2
2014 4
2015 4
2016 10
2017 6
2018 7
2019 5
2020 7
2021 6
2022 9
2023 5
2024 2

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Page 1
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Konermann S, et al. Among authors: nishimasu h. Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10. Nature. 2015. PMID: 25494202 Free PMC article.
Crystal structure of Cas9 in complex with guide RNA and target DNA.
Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O. Nishimasu H, et al. Cell. 2014 Feb 27;156(5):935-49. doi: 10.1016/j.cell.2014.02.001. Epub 2014 Feb 13. Cell. 2014. PMID: 24529477 Free PMC article.
RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Strecker J, Demircioglu FE, Li D, Faure G, Wilkinson ME, Gootenberg JS, Abudayyeh OO, Nishimasu H, Macrae RK, Zhang F. Strecker J, et al. Among authors: nishimasu h. Science. 2022 Nov 25;378(6622):874-881. doi: 10.1126/science.add7450. Epub 2022 Nov 3. Science. 2022. PMID: 36423276 Free PMC article.
Engineered CRISPR-Cas9 nuclease with expanded targeting space.
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Nishimasu H, et al. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. Science. 2018. PMID: 30166441 Free PMC article.
Structure of the miniature type V-F CRISPR-Cas effector enzyme.
Takeda SN, Nakagawa R, Okazaki S, Hirano H, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K, Nishimasu H, Nureki O. Takeda SN, et al. Among authors: nishimasu h. Mol Cell. 2021 Feb 4;81(3):558-570.e3. doi: 10.1016/j.molcel.2020.11.035. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333018 Free article.
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA.
Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O. Yamano T, et al. Among authors: nishimasu h. Cell. 2016 May 5;165(4):949-62. doi: 10.1016/j.cell.2016.04.003. Epub 2016 Apr 21. Cell. 2016. PMID: 27114038 Free PMC article.
Structure and engineering of the minimal type VI CRISPR-Cas13bt3.
Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K, Zhang F, Nishimasu H, Nureki O. Nakagawa R, et al. Among authors: nishimasu h. Mol Cell. 2022 Sep 1;82(17):3178-3192.e5. doi: 10.1016/j.molcel.2022.08.001. Epub 2022 Aug 25. Mol Cell. 2022. PMID: 36027912 Free PMC article.
Programmable RNA writing with trans-splicing.
Schmitt-Ulms C, Kayabolen A, Manero-Carranza M, Zhou N, Donnelly K, Nuccio SP, Kato K, Nishimasu H, Gootenberg JS, Abudayyeh OO. Schmitt-Ulms C, et al. Among authors: nishimasu h. bioRxiv [Preprint]. 2024 Feb 1:2024.01.31.578223. doi: 10.1101/2024.01.31.578223. bioRxiv. 2024. PMID: 38352602 Free PMC article. Preprint.
Structure of the IscB-ωRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9.
Kato K, Okazaki S, Kannan S, Altae-Tran H, Esra Demircioglu F, Isayama Y, Ishikawa J, Fukuda M, Macrae RK, Nishizawa T, Makarova KS, Koonin EV, Zhang F, Nishimasu H. Kato K, et al. Among authors: nishimasu h. Nat Commun. 2022 Nov 7;13(1):6719. doi: 10.1038/s41467-022-34378-3. Nat Commun. 2022. PMID: 36344504 Free PMC article.
78 results