Niswender CM[au] - Search Results

Year	Number of Results
1998	2
1999	3
2001	2
2002	2
2005	2
2006	1
2007	3
2008	9
2009	14
2010	27
2011	15
2012	30
2013	37
2014	21
2015	26
2016	24
2017	23
2018	24
2019	20
2020	7
2021	4

1

Metabotropic glutamate receptors: physiology, pharmacology, and disease.

Niswender CM, Conn PJ. Niswender CM, et al. Annu Rev Pharmacol Toxicol. 2010;50:295-322. doi: 10.1146/annurev.pharmtox.011008.145533. Annu Rev Pharmacol Toxicol. 2010. PMID: 20055706 Free PMC article. Review.

2

A Coordinated Attack: Rett Syndrome Therapeutic Development.

Gogliotti RG, Niswender CM. Gogliotti RG, et al. Among authors: niswender cm. Trends Pharmacol Sci. 2019 Apr;40(4):233-236. doi: 10.1016/j.tips.2019.02.007. Trends Pharmacol Sci. 2019. PMID: 30905360 Free PMC article. Review.

3

Phenotypic profiling of mGlu₇ knockout mice reveals new implications for neurodevelopmental disorders.

Fisher NM, Gould RW, Gogliotti RG, McDonald AJ, Badivuku H, Chennareddy S, Buch AB, Moore AM, Jenkins MT, Robb WH, Lindsley CW, Jones CK, Conn PJ, Niswender CM. Fisher NM, et al. Among authors: niswender cm. Genes Brain Behav. 2020 Sep;19(7):e12654. doi: 10.1111/gbb.12654. Epub 2020 Apr 14. Genes Brain Behav. 2020. PMID: 32248644 Free PMC article.

4

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.

Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC. Wu H, et al. Among authors: niswender cm. Science. 2014 Apr 4;344(6179):58-64. doi: 10.1126/science.1249489. Epub 2014 Mar 6. Science. 2014. PMID: 24603153 Free PMC article.

5

Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M₄ positive allosteric modulator (PAM) chemotype.

Temple KJ, Engers JL, Long MF, Watson KJ, Chang S, Luscombe VB, Jenkins MT, Rodriguez AL, Niswender CM, Bridges TM, Conn PJ, Engers DW, Lindsley CW. Temple KJ, et al. Among authors: niswender cm. Bioorg Med Chem Lett. 2020 Feb 1;30(3):126812. doi: 10.1016/j.bmcl.2019.126812. Epub 2019 Nov 13. Bioorg Med Chem Lett. 2020. PMID: 31784320

6

Discovery of structurally distinct tricyclic M₄ positive allosteric modulator (PAM) chemotypes.

Temple KJ, Long MF, Engers JL, Watson KJ, Chang S, Luscombe VB, Rodriguez AL, Niswender CM, Bridges TM, Conn PJ, Engers DW, Lindsley CW. Temple KJ, et al. Among authors: niswender cm. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126811. doi: 10.1016/j.bmcl.2019.126811. Epub 2019 Nov 11. Bioorg Med Chem Lett. 2020. PMID: 31787491

7

Challenges in the Discovery and Optimization of mGlu_2/4 Heterodimer Positive Allosteric Modulators.

Fulton MG, Loch MT, Cuoco CA, Rodriguez AL, Days E, Vinson PN, Kozek KA, Weaver CD, Blobaum AL, Conn PJ, Niswender CM, Lindsley CW. Fulton MG, et al. Among authors: niswender cm. Lett Drug Des Discov. 2019 Dec;16(12):1387-1394. doi: 10.2174/1570180815666181017131349. Lett Drug Des Discov. 2019. PMID: 32201485 Free PMC article.

8

Synthesis and SAR of a series of mGlu₇ NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core.

Kalbfleisch JJ, Reed CW, Park C, Spearing PK, Quitalig MC, Jenkins MT, Rodriguez AL, Blobaum AL, Conn PJ, Niswender CM, Lindsley CW. Kalbfleisch JJ, et al. Among authors: niswender cm. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127529. doi: 10.1016/j.bmcl.2020.127529. Epub 2020 Sep 2. Bioorg Med Chem Lett. 2020. PMID: 32890686

9

Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu₇ Positive Allosteric Modulator Tool Compound.

Reed CW, Kalbfleisch JJ, Wong MJ, Washecheck JP, Hunter A, Rodriguez AL, Blobaum AL, Conn PJ, Niswender CM, Lindsley CW. Reed CW, et al. Among authors: niswender cm. ACS Med Chem Lett. 2020 Aug 20;11(9):1773-1779. doi: 10.1021/acsmedchemlett.0c00432. eCollection 2020 Sep 10. ACS Med Chem Lett. 2020. PMID: 32944146

10

Discovery of a novel 3,4-dimethylcinnoline carboxamide M₄ positive allosteric modulator (PAM) chemotype via scaffold hopping.

Temple KJ, Engers JL, Long MF, Gregro AR, Watson KJ, Chang S, Jenkins MT, Luscombe VB, Rodriguez AL, Niswender CM, Bridges TM, Conn PJ, Engers DW, Lindsley CW. Temple KJ, et al. Among authors: niswender cm. Bioorg Med Chem Lett. 2019 Nov 1;29(21):126678. doi: 10.1016/j.bmcl.2019.126678. Epub 2019 Sep 10. Bioorg Med Chem Lett. 2019. PMID: 31537424

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