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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1995 3
1996 1
1997 1
1998 5
1999 8
2000 6
2001 7
2002 5
2003 1
2004 1
2005 8
2006 8
2007 10
2008 6
2009 7
2010 11
2011 18
2012 16
2013 17
2014 10
2015 9
2016 22
2017 16
2018 16
2019 19
2020 7
2021 9
2022 11
2023 0
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240 results
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Page 1
Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Tsuchida CA, Zhang S, Doost MS, Zhao Y, Wang J, O'Brien E, Fang H, Li CP, Li D, Hai ZY, Chuck J, Brötzmann J, Vartoumian A, Burstein D, Chen XW, Nogales E, Doudna JA, Liu JG. Tsuchida CA, et al. Among authors: nogales e. Mol Cell. 2022 Mar 17;82(6):1199-1209.e6. doi: 10.1016/j.molcel.2022.02.002. Epub 2022 Feb 25. Mol Cell. 2022. PMID: 35219382 Free PMC article.
DNA interference states of the hypercompact CRISPR-CasΦ effector.
Pausch P, Soczek KM, Herbst DA, Tsuchida CA, Al-Shayeb B, Banfield JF, Nogales E, Doudna JA. Pausch P, et al. Among authors: nogales e. Nat Struct Mol Biol. 2021 Aug;28(8):652-661. doi: 10.1038/s41594-021-00632-3. Epub 2021 Aug 11. Nat Struct Mol Biol. 2021. PMID: 34381246 Free PMC article.
Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L, He L, Gupta ML Jr, Cowan NJ, Wang L. Feng R, et al. Among authors: nogales e. N Engl J Med. 2016 Jan 21;374(3):223-32. doi: 10.1056/NEJMoa1510791. N Engl J Med. 2016. PMID: 26789871 Free PMC article.
CRISPR-Cas9 bends and twists DNA to read its sequence.
Cofsky JC, Soczek KM, Knott GJ, Nogales E, Doudna JA. Cofsky JC, et al. Among authors: nogales e. Nat Struct Mol Biol. 2022 Apr;29(4):395-402. doi: 10.1038/s41594-022-00756-0. Epub 2022 Apr 14. Nat Struct Mol Biol. 2022. PMID: 35422516 Free PMC article.
CasX enzymes comprise a distinct family of RNA-guided genome editors.
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA. Liu JJ, et al. Among authors: nogales e. Nature. 2019 Feb;566(7743):218-223. doi: 10.1038/s41586-019-0908-x. Epub 2019 Feb 4. Nature. 2019. PMID: 30718774 Free PMC article.
Nogales E. Nogales E. Curr Biol. 2018 Oct 8;28(19):R1127-R1128. doi: 10.1016/j.cub.2018.07.016. Curr Biol. 2018. PMID: 30300591 Free PMC article. Review.
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Jinek M, et al. Among authors: nogales e. Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6. Science. 2014. PMID: 24505130 Free PMC article.
240 results