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A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice.

Mimche SM, Lee CM, Liu KH, Mimche PN, Harvey RD, Murphy TJ, Nyagode BA, Jones DP, Lamb TJ, Morgan ET. Mimche SM, et al. Among authors: nyagode ba. Malar J. 2019 Jul 12;18(1):234. doi: 10.1186/s12936-019-2860-5. Malar J. 2019. PMID: 31299982 Free PMC article.

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Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice.

Merrell MD, Nyagode BA, Clarke JD, Cherrington NJ, Morgan ET. Merrell MD, et al. Among authors: nyagode ba. Drug Metab Dispos. 2014 Apr;42(4):596-602. doi: 10.1124/dmd.113.055525. Epub 2013 Dec 30. Drug Metab Dispos. 2014. PMID: 24378326 Free PMC article.

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Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.

Nyagode BA, Williams IR, Morgan ET. Nyagode BA, et al. Inflammation. 2014 Jun;37(3):893-907. doi: 10.1007/s10753-013-9809-6. Inflammation. 2014. PMID: 24413902 Free PMC article.

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Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6- and interferon-{gamma}-null mice.

Nyagode BA, Lee CM, Morgan ET. Nyagode BA, et al. J Pharmacol Exp Ther. 2010 Nov;335(2):480-8. doi: 10.1124/jpet.110.171488. Epub 2010 Aug 18. J Pharmacol Exp Ther. 2010. PMID: 20719939 Free PMC article.

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Hepatic cytochrome P450s, phase II enzymes and nuclear receptors are downregulated in a Th2 environment during Schistosoma mansoni infection.

Mimche SM, Nyagode BA, Merrell MD, Lee CM, Prasanphanich NS, Cummings RD, Morgan ET. Mimche SM, et al. Among authors: nyagode ba. Drug Metab Dispos. 2014 Jan;42(1):134-40. doi: 10.1124/dmd.113.054957. Epub 2013 Oct 25. Drug Metab Dispos. 2014. PMID: 24163175 Free PMC article.

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Regulation of hepatic cytochrome P450 expression in mice with intestinal or systemic infections of citrobacter rodentium.

Chaluvadi MR, Kinloch RD, Nyagode BA, Richardson TA, Raynor MJ, Sherman M, Antonovic L, Strobel HW, Dillehay DL, Morgan ET. Chaluvadi MR, et al. Among authors: nyagode ba. Drug Metab Dispos. 2009 Feb;37(2):366-74. doi: 10.1124/dmd.108.024240. Epub 2008 Oct 29. Drug Metab Dispos. 2009. PMID: 18971315 Free PMC article.

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TLR4-dependent and -independent regulation of hepatic cytochrome P450 in mice with chemically induced inflammatory bowel disease.

Chaluvadi MR, Nyagode BA, Kinloch RD, Morgan ET. Chaluvadi MR, et al. Among authors: nyagode ba. Biochem Pharmacol. 2009 Feb 1;77(3):464-71. doi: 10.1016/j.bcp.2008.10.029. Epub 2008 Nov 6. Biochem Pharmacol. 2009. PMID: 19027721 Free PMC article.

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Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus).

Nyagode BA, James MO, Kleinow KM. Nyagode BA, et al. Toxicol Sci. 2009 Apr;108(2):320-9. doi: 10.1093/toxsci/kfp018. Epub 2009 Jan 29. Toxicol Sci. 2009. PMID: 19181613 Free PMC article.

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Selective modulation of hepatic cytochrome P450 and flavin monooxygenase 3 expression during citrobacter rodentium infection in severe combined immune-deficient mice.

Nyagode BA, Watkins WJ, Kinloch RD, Morgan ET. Nyagode BA, et al. Drug Metab Dispos. 2012 Oct;40(10):1894-9. doi: 10.1124/dmd.112.046557. Epub 2012 Jun 27. Drug Metab Dispos. 2012. PMID: 22745333 Free PMC article.

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Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions.

Nyagode BA, Jahangardi R, Merrell MD, Tansey MG, Morgan ET. Nyagode BA, et al. Pharmacol Res Perspect. 2014 Feb 1;2(1):e00027. doi: 10.1002/prp2.27. Pharmacol Res Perspect. 2014. PMID: 24707356 Free PMC article.

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