Nygård SB[au] - Search Results

Year	Number of Results
2011	1
2012	2
2013	5
2014	1
2015	4
2016	2
2022	1

1

Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.

Stenvang J, Kümler I, Nygård SB, Smith DH, Nielsen D, Brünner N, Moreira JM. Stenvang J, et al. Among authors: nygard sb. Front Oncol. 2013 Dec 25;3:313. doi: 10.3389/fonc.2013.00313. Front Oncol. 2013. PMID: 24400218 Free PMC article. Review.

2

Predictive biomarkers with potential of converting conventional chemotherapy to targeted therapy in patients with metastatic colorectal cancer.

Jensen NF, Smith DH, Nygård SB, Rømer MU, Nielsen KV, Brünner N. Jensen NF, et al. Among authors: nygard sb. Scand J Gastroenterol. 2012 Mar;47(3):340-55. doi: 10.3109/00365521.2012.640835. Epub 2011 Dec 19. Scand J Gastroenterol. 2012. PMID: 22181013 Review.

3

Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer.

Kümler I, Balslev E, Poulsen TS, Nielsen SL, Nygård SB, Rømer MU, Christensen IJ, Høgdall E, Moreira J, Nielsen DL, Brünner N, Stenvang J. Kümler I, et al. Among authors: nygard sb. Int J Cancer. 2015 Oct 15;137(8):2000-6. doi: 10.1002/ijc.29556. Epub 2015 Apr 27. Int J Cancer. 2015. PMID: 25855483 Free article.

4

A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification.

Tarpgaard LS, Qvortrup C, Nygård SB, Nielsen SL, Andersen DR, Jensen NF, Stenvang J, Detlefsen S, Brünner N, Pfeiffer P. Tarpgaard LS, et al. Among authors: nygard sb. BMC Cancer. 2016 Feb 11;16:91. doi: 10.1186/s12885-016-2124-5. BMC Cancer. 2016. PMID: 26867764 Free PMC article. Clinical Trial.

5

In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic.

Säll C, Alifrangis L, Dahl K, Friedrichsen MH, Nygård SB, Kristensen K. Säll C, et al. Among authors: nygard sb. Drug Metab Dispos. 2022 Jun 9:DMD-AR-2022-000865. doi: 10.1124/dmd.122.000865. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35680133 Free article.

6

Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance.

Jensen NF, Stenvang J, Beck MK, Hanáková B, Belling KC, Do KN, Viuff B, Nygård SB, Gupta R, Rasmussen MH, Tarpgaard LS, Hansen TP, Budinská E, Pfeiffer P, Bosman F, Tejpar S, Roth A, Delorenzi M, Andersen CL, Rømer MU, Brünner N, Moreira JM. Jensen NF, et al. Among authors: nygard sb. Mol Oncol. 2015 Jun;9(6):1169-85. doi: 10.1016/j.molonc.2015.02.008. Epub 2015 Feb 24. Mol Oncol. 2015. PMID: 25759163 Free PMC article.

7

DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer.

Nygård SB, Vainer B, Nielsen SL, Bosman F, Tejpar S, Roth A, Delorenzi M, Brünner N, Budinska E. Nygård SB, et al. Clin Cancer Res. 2016 Apr 1;22(7):1621-31. doi: 10.1158/1078-0432.CCR-15-0561. Epub 2015 Nov 5. Clin Cancer Res. 2016. PMID: 26542057

8

Mechanisms of topoisomerase I (TOP1) gene copy number increase in a stage III colorectal cancer patient cohort.

Smith DH, Christensen IJ, Jensen NF, Markussen B, Rømer MU, Nygård SB, Müller S, Nielsen HJ, Brünner N, Nielsen KV. Smith DH, et al. Among authors: nygard sb. PLoS One. 2013;8(4):e60613. doi: 10.1371/journal.pone.0060613. Epub 2013 Apr 5. PLoS One. 2013. PMID: 23577133 Free PMC article.

9

Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer.

Nygård SB, Christensen IJ, Nielsen SL, Nielsen HJ, Brünner N, Spindler KL. Nygård SB, et al. Scand J Gastroenterol. 2014 Jan;49(1):84-91. doi: 10.3109/00365521.2013.856464. Epub 2013 Nov 21. Scand J Gastroenterol. 2014. PMID: 24256029

10

Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer.

Nygård SB, Christensen IJ, Smith DH, Nielsen SL, Jensen NF, Nielsen HJ, Vainer B, Brünner N. Nygård SB, et al. Scand J Gastroenterol. 2013 Dec;48(12):1436-43. doi: 10.3109/00365521.2013.848230. Epub 2013 Oct 21. Scand J Gastroenterol. 2013. PMID: 24138107

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