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2019 5
2020 3
2021 2
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International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.
Read C, Nyimanu D, Williams TL, Huggins DJ, Sulentic P, Macrae RGC, Yang P, Glen RC, Maguire JJ, Davenport AP. Read C, et al. Among authors: nyimanu d. Pharmacol Rev. 2019 Oct;71(4):467-502. doi: 10.1124/pr.119.017533. Pharmacol Rev. 2019. PMID: 31492821 Free PMC article. Review.
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.
Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Glen RC, Morrell NW, Davenport AP, Maguire JJ. Yang P, et al. Among authors: nyimanu d. Br J Pharmacol. 2019 May;176(9):1206-1221. doi: 10.1111/bph.14603. Epub 2019 Apr 1. Br J Pharmacol. 2019. PMID: 30710493 Free PMC article.
Apelin peptides linked to anti-serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo.
Read C, Yang P, Kuc RE, Nyimanu D, Williams TL, Glen RC, Holt LJ, Arulanantham H, Smart A, Davenport AP, Maguire JJ. Read C, et al. Among authors: nyimanu d. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6:96-103. doi: 10.1111/bcpt.13227. Epub 2019 Apr 10. Basic Clin Pharmacol Toxicol. 2020. PMID: 30901161 Free article.
The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.
Read C, Nyimanu D, Yang P, Kuc RE, Williams TL, Fitzpatrick CM, Foster R, Glen RC, Maguire JJ, Davenport AP. Read C, et al. Among authors: nyimanu d. Front Pharmacol. 2021 Jan 21;11:588669. doi: 10.3389/fphar.2020.588669. eCollection 2020. Front Pharmacol. 2021. PMID: 33716722 Free PMC article.