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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1987 2
1989 2
1990 3
1991 1
1992 3
1993 4
1994 1
1995 12
1996 9
1997 10
1998 4
1999 4
2000 13
2001 8
2002 8
2003 14
2004 12
2005 8
2006 11
2007 18
2008 16
2009 20
2010 17
2011 21
2012 14
2013 22
2014 19
2015 17
2016 20
2017 23
2018 16
2019 10
2020 18
2021 19
2022 10
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385 results
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Page 1
Trained immunity: A program of innate immune memory in health and disease.
Netea MG, Joosten LA, Latz E, Mills KH, Natoli G, Stunnenberg HG, O'Neill LA, Xavier RJ. Netea MG, et al. Among authors: o neill la. Science. 2016 Apr 22;352(6284):aaf1098. doi: 10.1126/science.aaf1098. Epub 2016 Apr 21. Science. 2016. PMID: 27102489 Free PMC article. Review.
Macrophage Immunometabolism: Where Are We (Going)?
Van den Bossche J, O'Neill LA, Menon D. Van den Bossche J, et al. Among authors: o neill la. Trends Immunol. 2017 Jun;38(6):395-406. doi: 10.1016/j.it.2017.03.001. Epub 2017 Apr 7. Trends Immunol. 2017. PMID: 28396078 Review.
A guide to immunometabolism for immunologists.
O'Neill LA, Kishton RJ, Rathmell J. O'Neill LA, et al. Nat Rev Immunol. 2016 Sep;16(9):553-65. doi: 10.1038/nri.2016.70. Epub 2016 Jul 11. Nat Rev Immunol. 2016. PMID: 27396447 Free PMC article. Review.
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: o neill la. Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22. Cell. 2016. PMID: 27667687 Free PMC article.
The Role of HIF in Immunity and Inflammation.
McGettrick AF, O'Neill LAJ. McGettrick AF, et al. Among authors: o neill laj. Cell Metab. 2020 Oct 6;32(4):524-536. doi: 10.1016/j.cmet.2020.08.002. Epub 2020 Aug 26. Cell Metab. 2020. PMID: 32853548 Free article. Review.
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA. Tannahill GM, et al. Among authors: o neill la. Nature. 2013 Apr 11;496(7444):238-42. doi: 10.1038/nature11986. Epub 2013 Mar 24. Nature. 2013. PMID: 23535595 Free PMC article.
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Among authors: o neill la. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: o neill la. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
Mitochondria are the powerhouses of immunity.
Mills EL, Kelly B, O'Neill LAJ. Mills EL, et al. Among authors: o neill laj. Nat Immunol. 2017 Apr 18;18(5):488-498. doi: 10.1038/ni.3704. Nat Immunol. 2017. PMID: 28418387 Review.
Metabolic regulation of NLRP3.
Hughes MM, O'Neill LAJ. Hughes MM, et al. Among authors: o neill laj. Immunol Rev. 2018 Jan;281(1):88-98. doi: 10.1111/imr.12608. Immunol Rev. 2018. PMID: 29247992 Review.
385 results