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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1953 1
1963 3
1964 1
1965 1
1966 1
1967 2
1969 3
1970 2
1972 2
1973 2
1974 2
1976 1
1978 2
1979 2
1980 2
1982 5
1983 1
1984 3
1985 6
1986 3
1987 5
1988 5
1989 3
1991 1
1992 3
1993 2
1994 10
1995 9
1996 12
1997 11
1998 5
1999 13
2000 15
2001 9
2002 7
2003 19
2004 11
2005 7
2006 11
2007 13
2008 16
2009 17
2010 22
2011 18
2012 16
2013 12
2014 18
2015 23
2016 11
2017 19
2018 32
2019 46
2020 33
2021 31
2022 42
2023 26
2024 14

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Search Results

552 results

Results by year

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Page 1
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity.
Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, Dorsey JF, Christian KM, Binder ZA, Nasrallah M, Brem S, O'Rourke DM, Ming GL, Song H. Jacob F, et al. Among authors: o rourke dm. Cell. 2020 Jan 9;180(1):188-204.e22. doi: 10.1016/j.cell.2019.11.036. Epub 2019 Dec 26. Cell. 2020. PMID: 31883794 Free PMC article.
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV. O'Rourke DM, et al. Sci Transl Med. 2017 Jul 19;9(399):eaaa0984. doi: 10.1126/scitranslmed.aaa0984. Sci Transl Med. 2017. PMID: 28724573 Free PMC article. Clinical Trial.
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.
Bagley SJ, Logun M, Fraietta JA, Wang X, Desai AS, Bagley LJ, Nabavizadeh A, Jarocha D, Martins R, Maloney E, Lledo L, Stein C, Marshall A, Leskowitz R, Jadlowsky JK, Christensen S, Oner BS, Plesa G, Brennan A, Gonzalez V, Chen F, Sun Y, Gladney W, Barrett D, Nasrallah MP, Hwang WT, Ming GL, Song H, Siegel DL, June CH, Hexner EO, Binder ZA, O'Rourke DM. Bagley SJ, et al. Among authors: o rourke dm. Nat Med. 2024 May;30(5):1320-1329. doi: 10.1038/s41591-024-02893-z. Epub 2024 Mar 13. Nat Med. 2024. PMID: 38480922 Clinical Trial.
Nontraditional Species.
O’Rourke DP, Cox JD, Baumann DP. O’Rourke DP, et al. In: Weichbrod RH, Thompson GA, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 25. In: Weichbrod RH, Thompson GA, Norton JN, editors. Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 25. PMID: 29787227 Free Books & Documents. Review.
CAR T Cells.
Tudor T, Binder ZA, O'Rourke DM. Tudor T, et al. Among authors: o rourke dm. Neurosurg Clin N Am. 2021 Apr;32(2):249-263. doi: 10.1016/j.nec.2020.12.005. Epub 2021 Feb 18. Neurosurg Clin N Am. 2021. PMID: 33781506 Review.
Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors.
Yin Y, Rodriguez JL, Li N, Thokala R, Nasrallah MP, Hu L, Zhang L, Zhang JV, Logun MT, Kainth D, Haddad L, Zhao Y, Wu T, Johns EX, Long Y, Liang H, Qi J, Zhang X, Binder ZA, Lin Z, O'Rourke DM. Yin Y, et al. Among authors: o rourke dm. Mol Ther. 2022 Jul 6;30(7):2537-2553. doi: 10.1016/j.ymthe.2022.05.011. Epub 2022 May 14. Mol Ther. 2022. PMID: 35570396 Free PMC article.
Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial.
Bagley SJ, Binder ZA, Lamrani L, Marinari E, Desai AS, Nasrallah MP, Maloney E, Brem S, Lustig RA, Kurtz G, Alonso-Basanta M, Bonté PE, Goudot C, Richer W, Piaggio E, Kothari S, Guyonnet L, Guerin CL, Waterfall JJ, Mohan S, Hwang WT, Tang OY, Logun M, Bhattacharyya M, Markowitz K, Delman D, Marshall A, Wherry EJ, Amigorena S, Beatty GL, Brogdon JL, Hexner E, Migliorini D, Alanio C, O'Rourke DM. Bagley SJ, et al. Among authors: o rourke dm. Nat Cancer. 2024 Mar;5(3):517-531. doi: 10.1038/s43018-023-00709-6. Epub 2024 Jan 12. Nat Cancer. 2024. PMID: 38216766 Clinical Trial.
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB. Lu C, et al. Among authors: o rourke dm. Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
Live Organoid Cyclic Imaging.
Reynolds DE, Sun Y, Wang X, Vallapureddy P, Lim J, Pan M, Fernandez Del Castillo A, Carlson JCT, Sellmyer MA, Nasrallah M, Binder Z, O'Rourke DM, Ming GL, Song H, Ko J. Reynolds DE, et al. Among authors: o rourke dm. Adv Sci (Weinh). 2024 Apr;11(14):e2309289. doi: 10.1002/advs.202309289. Epub 2024 Feb 7. Adv Sci (Weinh). 2024. PMID: 38326078 Free PMC article.
552 results