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27 results

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Page 1
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.
Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, Olsson L, Orsmark-Pietras C, von Palffy S, Askmyr M, Rissler M, Schrappe M, Cario G, Castor A, Pronk CJ, Behrendtz M, Mitelman F, Johansson B, Paulsson K, Andersson AK, Fontes M, Fioretos T. Lilljebjörn H, et al. Among authors: orsmark pietras c. Nat Commun. 2016 Jun 6;7:11790. doi: 10.1038/ncomms11790. Nat Commun. 2016. PMID: 27265895 Free PMC article.
Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia.
Sandén C, Landberg N, Peña-Martínez P, Thorsson H, Daga S, Puente-Moncada N, Rodriguez-Zabala M, von Palffy S, Rissler M, Lazarevic V, Juliusson G, Ohlin M, Hyrenius-Wittsten A, Orsmark-Pietras C, Lilljebjörn H, Ågerstam H, Fioretos T. Sandén C, et al. Among authors: orsmark pietras c. Nat Cancer. 2025 Nov;6(11):1821-1838. doi: 10.1038/s43018-025-01054-6. Epub 2025 Oct 3. Nat Cancer. 2025. PMID: 41044242 Free PMC article.
Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases.
Thorsson H, Henningsson R, Puente-Moncada N, Peña-Martínez P, Sjöström L, Ågerstam H, Sandén C, Rissler M, Castor A, Marquart H, Modvig S, Paulsson K, Pronk CJ, Schmiegelow K, Hyrenius-Wittsten A, Orsmark-Pietras C, Lilljebjörn H, Fioretos T. Thorsson H, et al. Among authors: orsmark pietras c. Blood. 2024 Sep 26;144(13):1399-1411. doi: 10.1182/blood.2023021705. Blood. 2024. PMID: 38968149 Free PMC article.
The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes.
Lilljebjörn H, Peña-Martínez P, Thorsson H, Henningsson R, Rissler M, Landberg N, Puente-Moncada N, von Palffy S, Rissler V, Stanek P, Desponds J, Zhong X, Juliusson G, Lazarevic V, Lehmann S, Fontes M, Ågerstam H, Sandén C, Orsmark-Pietras C, Fioretos T. Lilljebjörn H, et al. Among authors: orsmark pietras c. Nat Commun. 2025 Nov 25;16(1):10592. doi: 10.1038/s41467-025-66546-6. Nat Commun. 2025. PMID: 41290664 Free PMC article.
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML.
von Palffy S, Thorsson H, Peña-Martínez P, Puente-Moncada N, Sandén C, Blom AM, Henningsson R, Juliusson G, King B, Landberg N, Lazarevic V, Orsmark-Pietras C, Rissler M, Rissler V, Ågerstam H, Järås M, Lilljebjörn H, Fioretos T. von Palffy S, et al. Among authors: orsmark pietras c. Blood Adv. 2023 Apr 11;7(7):1204-1218. doi: 10.1182/bloodadvances.2022007682. Blood Adv. 2023. PMID: 36383712 Free PMC article.
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer.
Wadensten E, Wessman S, Abel F, Diaz De Ståhl T, Tesi B, Orsmark Pietras C, Arvidsson L, Taylan F, Fransson S, Vogt H, Poluha A, Pradhananga S, Hellberg M, Lagerstedt-Robinson K, Raj Somarajan P, Samuelsson S, Orrsjö S, Maqbool K, Henning K, Strid T, Ek T, Fagman H, Olsson Bontell T, Martinsson T, Puls F, Kogner P, Wirta V, Pronk CJ, Wille J, Rosenquist R, Nistér M, Mertens F, Sabel M, Norén-Nyström U, Grillner P, Nordgren A, Ljungman G, Sandgren J, Gisselsson D; Genomic Medicine Sweden Childhood Cancer Working Group. Wadensten E, et al. Among authors: orsmark pietras c. JCO Precis Oncol. 2023 Jun;7:e2300039. doi: 10.1200/PO.23.00039. JCO Precis Oncol. 2023. PMID: 37384868 Free PMC article.
Clonal competition within complex evolutionary hierarchies shapes AML over time.
Sandén C, Lilljebjörn H, Orsmark Pietras C, Henningsson R, Saba KH, Landberg N, Thorsson H, von Palffy S, Peña-Martinez P, Högberg C, Rissler M, Gisselsson D, Lazarevic V, Juliusson G, Ågerstam H, Fioretos T. Sandén C, et al. Among authors: orsmark pietras c. Nat Commun. 2020 Feb 5;11(1):579. doi: 10.1038/s41467-019-14106-0. Nat Commun. 2020. PMID: 32024830 Free PMC article.
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture-Based Gene Panel.
Orsmark-Pietras C, Lyander A, Ladenvall C, Hallström B, Staffas A, Awier H, Krstic A, Baliakas P, Barbany G, Håkansson CB, Gellerbring A, Hagström A, Hellström-Lindberg E, Juliusson G, Lazarevic V, Munters A, Pandzic T, Wadelius M, Ås J, Fogelstrand L, Wirta V, Rosenquist R, Cavelier L, Fioretos T; SciLifeLab Clinical Genomics Platform and Genomic Medicine Sweden. Orsmark-Pietras C, et al. Genes Chromosomes Cancer. 2024 Jul;63(7):e23257. doi: 10.1002/gcc.23257. Genes Chromosomes Cancer. 2024. PMID: 39031442
27 results