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1963 1
2012 1
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Page 1
Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands.
Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, Abbruscato TJ, Trippier PC, Neugebauer V, German NA. Shahbazi Nia S, et al. Among authors: obeng s. Eur J Med Chem. 2023 Jun 5;254:115309. doi: 10.1016/j.ejmech.2023.115309. Epub 2023 Mar 29. Eur J Med Chem. 2023. PMID: 37054561 Free PMC article.
In vitro and in vivo pharmacology of kratom.
Hiranita T, Obeng S, Sharma A, Wilkerson JL, McCurdy CR, McMahon LR. Hiranita T, et al. Among authors: obeng s. Adv Pharmacol. 2022;93:35-76. doi: 10.1016/bs.apha.2021.10.001. Epub 2021 Dec 13. Adv Pharmacol. 2022. PMID: 35341571
Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in Rats.
Kamble SH, Obeng S, León F, Restrepo LF, King TI, Berthold EC, Kanumuri SRR, Gamez-Jimenez LR, Pallares VLC, Patel A, Ho NP, Hampson A, McCurdy CR, McMahon LR, Wilkerson JL, Sharma A, Hiranita T. Kamble SH, et al. Among authors: obeng s. J Pharmacol Exp Ther. 2023 Jun;385(3):180-192. doi: 10.1124/jpet.122.001525. Epub 2023 Apr 5. J Pharmacol Exp Ther. 2023. PMID: 37019472 Free PMC article.
Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.
León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, McMahon LR, McCurdy CR. León F, et al. Among authors: obeng s. J Med Chem. 2021 Sep 23;64(18):13510-13523. doi: 10.1021/acs.jmedchem.1c00726. Epub 2021 Sep 1. J Med Chem. 2021. PMID: 34467758 Free PMC article.
Anionic phospholipids control mechanisms of GPCR-G protein recognition.
Thakur N, Ray AP, Sharp L, Jin B, Duong A, Pour NG, Obeng S, Wijesekara AV, Gao ZG, McCurdy CR, Jacobson KA, Lyman E, Eddy MT. Thakur N, et al. Among authors: obeng s. Nat Commun. 2023 Feb 13;14(1):794. doi: 10.1038/s41467-023-36425-z. Nat Commun. 2023. PMID: 36781870 Free PMC article.
Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition.
Thakur N, Ray AP, Sharp L, Jin B, Duong A, Pour NG, Obeng S, Wijesekara AV, Gao ZG, McCurdy CR, Jacobson KA, Lyman E, Eddy MT. Thakur N, et al. Among authors: obeng s. bioRxiv [Preprint]. 2023 Jan 13:2023.01.11.523010. doi: 10.1101/2023.01.11.523010. bioRxiv. 2023. PMID: 36711594 Free PMC article. Updated. Preprint.
Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists.
Pagare PP, Li M, Zheng Y, Kulkarni AS, Obeng S, Huang B, Ruiz C, Gillespie JC, Mendez RE, Stevens DL, Poklis JL, Halquist MS, Dewey WL, Selley DE, Zhang Y. Pagare PP, et al. Among authors: obeng s. J Med Chem. 2022 Mar 24;65(6):5095-5112. doi: 10.1021/acs.jmedchem.2c00087. Epub 2022 Mar 7. J Med Chem. 2022. PMID: 35255685 Free PMC article.
Interactive Effects of µ-Opioid and Adrenergic-α 2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine.
Obeng S, Leon F, Patel A, Zuarth Gonzalez JD, Chaves Da Silva L, Restrepo LF, Gamez-Jimenez LR, Ho NP, Guerrero Calvache MP, Pallares VLC, Helmes JA, Shiomitsu SK, Soto PL, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. Obeng S, et al. J Pharmacol Exp Ther. 2022 Dec;383(3):182-198. doi: 10.1124/jpet.122.001192. Epub 2022 Sep 24. J Pharmacol Exp Ther. 2022. PMID: 36153006 Free PMC article.
34 results