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Development, maintenance and disruption of the blood-brain barrier.

Obermeier B, Daneman R, Ransohoff RM. Obermeier B, et al. Nat Med. 2013 Dec;19(12):1584-96. doi: 10.1038/nm.3407. Epub 2013 Dec 5. Nat Med. 2013. PMID: 24309662 Free PMC article. Review.

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The blood-brain barrier.

Obermeier B, Verma A, Ransohoff RM. Obermeier B, et al. Handb Clin Neurol. 2016;133:39-59. doi: 10.1016/B978-0-444-63432-0.00003-7. Handb Clin Neurol. 2016. PMID: 27112670 Review.

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Multifunctional Poly(ethylene glycol)s.

Obermeier B, Wurm F, Mangold C, Frey H. Obermeier B, et al. Angew Chem Int Ed Engl. 2011 Aug 22;50(35):7988-97. doi: 10.1002/anie.201100027. Epub 2011 Jul 12. Angew Chem Int Ed Engl. 2011. PMID: 21751305 Review.

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Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro.

Takeshita Y, Obermeier B, Cotleur AC, Spampinato SF, Shimizu F, Yamamoto E, Sano Y, Kryzer TJ, Lennon VA, Kanda T, Ransohoff RM. Takeshita Y, et al. Among authors: obermeier b. Neurol Neuroimmunol Neuroinflamm. 2016 Dec 19;4(1):e311. doi: 10.1212/NXI.0000000000000311. eCollection 2017 Jan. Neurol Neuroimmunol Neuroinflamm. 2016. PMID: 28018943 Free PMC article.

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Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging.

Salman MM, Marsh G, Kusters I, Delincé M, Di Caprio G, Upadhyayula S, de Nola G, Hunt R, Ohashi KG, Gray T, Shimizu F, Sano Y, Kanda T, Obermeier B, Kirchhausen T. Salman MM, et al. Among authors: obermeier b. Front Bioeng Biotechnol. 2020 Sep 28;8:573775. doi: 10.3389/fbioe.2020.573775. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33117784 Free PMC article.

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Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins.

Brändle SM, Obermeier B, Senel M, Bruder J, Mentele R, Khademi M, Olsson T, Tumani H, Kristoferitsch W, Lottspeich F, Wekerle H, Hohlfeld R, Dornmair K. Brändle SM, et al. Among authors: obermeier b. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7864-9. doi: 10.1073/pnas.1522730113. Epub 2016 Jun 20. Proc Natl Acad Sci U S A. 2016. PMID: 27325759 Free PMC article.

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A perfused human blood-brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport.

Wevers NR, Kasi DG, Gray T, Wilschut KJ, Smith B, van Vught R, Shimizu F, Sano Y, Kanda T, Marsh G, Trietsch SJ, Vulto P, Lanz HL, Obermeier B. Wevers NR, et al. Among authors: obermeier b. Fluids Barriers CNS. 2018 Aug 31;15(1):23. doi: 10.1186/s12987-018-0108-3. Fluids Barriers CNS. 2018. PMID: 30165870 Free PMC article.

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Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica.

Shimizu F, Schaller KL, Owens GP, Cotleur AC, Kellner D, Takeshita Y, Obermeier B, Kryzer TJ, Sano Y, Kanda T, Lennon VA, Ransohoff RM, Bennett JL. Shimizu F, et al. Among authors: obermeier b. Sci Transl Med. 2017 Jul 5;9(397):eaai9111. doi: 10.1126/scitranslmed.aai9111. Sci Transl Med. 2017. PMID: 28679661 Free PMC article.

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Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation.

Beltrán E, Obermeier B, Moser M, Coret F, Simó-Castelló M, Boscá I, Pérez-Miralles F, Villar LM, Senel M, Tumani H, Hohlfeld R, Casanova B, Dornmair K. Beltrán E, et al. Among authors: obermeier b. Brain. 2014 Oct;137(Pt 10):2703-14. doi: 10.1093/brain/awu205. Epub 2014 Jul 23. Brain. 2014. PMID: 25060097

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Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin.

Obermeier B, Lovato L, Mentele R, Brück W, Forne I, Imhof A, Lottspeich F, Turk KW, Willis SN, Wekerle H, Hohlfeld R, Hafler DA, O'Connor KC, Dornmair K. Obermeier B, et al. J Neuroimmunol. 2011 Apr;233(1-2):245-8. doi: 10.1016/j.jneuroim.2011.01.010. Epub 2011 Feb 24. J Neuroimmunol. 2011. PMID: 21353315 Free PMC article.

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