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Mitochondrial lipidomes are tissue specific - low cholesterol contents relate to UCP1 activity.
Brunner S, Höring M, Liebisch G, Schweizer S, Scheiber J, Giansanti P, Hidrobo M, Hermeling S, Oeckl J, Prudente de Mello N, Perocchi F, Seeliger C, Strohmeyer A, Klingenspor M, Plagge J, Küster B, Burkhardt R, Janssen KP, Ecker J. Brunner S, et al. Among authors: oeckl j. Life Sci Alliance. 2024 Jun 6;7(8):e202402828. doi: 10.26508/lsa.202402828. Print 2024 Aug. Life Sci Alliance. 2024. PMID: 38843936 Free PMC article.
Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat.
Oeckl J, Janovska P, Adamcova K, Bardova K, Brunner S, Dieckmann S, Ecker J, Fromme T, Funda J, Gantert T, Giansanti P, Hidrobo MS, Kuda O, Kuster B, Li Y, Pohl R, Schmitt S, Schweizer S, Zischka H, Zouhar P, Kopecky J, Klingenspor M. Oeckl J, et al. Mol Metab. 2022 Jul;61:101499. doi: 10.1016/j.molmet.2022.101499. Epub 2022 Apr 22. Mol Metab. 2022. PMID: 35470094 Free PMC article.