Oitate M[au] - Search Results

Year	Number of Results
1971	1
2001	1
2006	2
2007	2
2009	1
2011	2
2012	1
2016	3
2019	1
2020	1
2023	0

1

DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1.

Ogitani Y, Aida T, Hagihara K, Yamaguchi J, Ishii C, Harada N, Soma M, Okamoto H, Oitate M, Arakawa S, Hirai T, Atsumi R, Nakada T, Hayakawa I, Abe Y, Agatsuma T. Ogitani Y, et al. Among authors: oitate m. Clin Cancer Res. 2016 Oct 15;22(20):5097-5108. doi: 10.1158/1078-0432.CCR-15-2822. Epub 2016 Mar 29. Clin Cancer Res. 2016. PMID: 27026201

2

Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice.

Okamoto H, Oitate M, Hagihara K, Shiozawa H, Furuta Y, Ogitani Y, Kuga H. Okamoto H, et al. Among authors: oitate m. Xenobiotica. 2020 Oct;50(10):1242-1250. doi: 10.1080/00498254.2020.1755909. Epub 2020 Apr 22. Xenobiotica. 2020. PMID: 32306807

3

Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity.

Ogitani Y, Hagihara K, Oitate M, Naito H, Agatsuma T. Ogitani Y, et al. Among authors: oitate m. Cancer Sci. 2016 Jul;107(7):1039-46. doi: 10.1111/cas.12966. Epub 2016 Jun 22. Cancer Sci. 2016. PMID: 27166974 Free PMC article.

4

Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys.

Nagai Y, Oitate M, Shiozawa H, Ando O. Nagai Y, et al. Among authors: oitate m. Xenobiotica. 2019 Sep;49(9):1086-1096. doi: 10.1080/00498254.2018.1531158. Epub 2019 Jan 4. Xenobiotica. 2019. PMID: 30351177

5

Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology.

Ogitani Y, Abe Y, Iguchi T, Yamaguchi J, Terauchi T, Kitamura M, Goto K, Goto M, Oitate M, Yukinaga H, Yabe Y, Nakada T, Masuda T, Morita K, Agatsuma T. Ogitani Y, et al. Among authors: oitate m. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5069-5072. doi: 10.1016/j.bmcl.2016.08.082. Epub 2016 Aug 27. Bioorg Med Chem Lett. 2016. PMID: 27599744

6

Mechanism for covalent binding of rofecoxib to elastin of rat aorta.

Oitate M, Hirota T, Takahashi M, Murai T, Miura S, Senoo A, Hosokawa T, Oonishi T, Ikeda T. Oitate M, et al. J Pharmacol Exp Ther. 2007 Mar;320(3):1195-203. doi: 10.1124/jpet.106.114447. Epub 2006 Dec 12. J Pharmacol Exp Ther. 2007. PMID: 17164475

7

Prediction of human pharmacokinetics of therapeutic monoclonal antibodies from simple allometry of monkey data.

Oitate M, Masubuchi N, Ito T, Yabe Y, Karibe T, Aoki T, Murayama N, Kurihara A, Okudaira N, Izumi T. Oitate M, et al. Drug Metab Pharmacokinet. 2011;26(4):423-30. doi: 10.2133/dmpk.dmpk-11-rg-011. Epub 2011 May 24. Drug Metab Pharmacokinet. 2011. PMID: 21606605 Free article.

8

Prediction of human plasma concentration-time profiles of monoclonal antibodies from monkey data by a species-invariant time method.

Oitate M, Nakayama S, Ito T, Kurihara A, Okudaira N, Izumi T. Oitate M, et al. Drug Metab Pharmacokinet. 2012;27(3):354-9. doi: 10.2133/dmpk.dmpk-11-sh-059. Epub 2011 Dec 6. Drug Metab Pharmacokinet. 2012. PMID: 22146109 Free article.

9

Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.

Oitate M, Hirota T, Murai T, Miura S, Ikeda T. Oitate M, et al. Drug Metab Dispos. 2007 Oct;35(10):1846-52. doi: 10.1124/dmd.107.016121. Epub 2007 Jul 9. Drug Metab Dispos. 2007. PMID: 17620346

10

CS-8958, a prodrug of the novel neuraminidase inhibitor R-125489, demonstrates a favorable long-retention profile in the mouse respiratory tract.

Koyama K, Takahashi M, Oitate M, Nakai N, Takakusa H, Miura S, Okazaki O. Koyama K, et al. Among authors: oitate m. Antimicrob Agents Chemother. 2009 Nov;53(11):4845-51. doi: 10.1128/AAC.00731-09. Epub 2009 Aug 17. Antimicrob Agents Chemother. 2009. PMID: 19687241 Free PMC article.

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