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A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT.
Betancourt Moreira K, Collier MP, Leitner A, Li KH, Lachapel ILS, McCarthy F, Opoku-Nsiah KA, Morales-Polanco F, Barbosa N, Gestaut D, Samant RS, Roh SH, Frydman J. Betancourt Moreira K, et al. Among authors: opoku nsiah ka. Mol Cell. 2023 Sep 7;83(17):3123-3139.e8. doi: 10.1016/j.molcel.2023.07.031. Epub 2023 Aug 24. Mol Cell. 2023. PMID: 37625406
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE. Ravalin M, et al. Among authors: opoku nsiah ka. Nat Chem Biol. 2019 Aug;15(8):786-794. doi: 10.1038/s41589-019-0322-6. Epub 2019 Jul 18. Nat Chem Biol. 2019. PMID: 31320752 Free PMC article.